Chiral discrimination is a new term for an old idea, going back at least to Pasteur and perhaps before. Where the pairinteraction energy of two molecules or ions is different for the two enantiomers of one acting on the same enantiomer of the other there is chiral discrimination. In its application to small molecules, at distances greater than closest approach, where the molecules had some freedom of rotation, the current revival of interest stems from the work of F.P. Dwyer and collaborators in the 1950’s . Since then theoretical papers have appeared and many new and precise experimental measurements have been made enabling magnitudes to be estimated. In the discussion to follow the main results and problems are surveyed. Much of the theory as well as the experimental basis has been reviewed quite recently [2,3]. These sources may be used for fuller accounts. In the following a wider viewpoint is attempted, with some emphasis on recent development.
KeywordsTartaric Acid Dispersion Interaction Transition Moment Multipole Moment Chiral Molecule
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