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Clinical Applications of Cardiac Tagging

  • Nathaniel Reichek
Chapter
Part of the Computational Imaging and Vision book series (CIVI, volume 23)

Abstract

In vitro assessment of myocardial contraction is possible in experimental models at many levels, from the classical papillary muscle model down to video tracking of deformation of individual loaded or unloaded myocytes. However, in vivo assessment of myocardial contraction remains critically important for understanding disease pathophysiology and responses to potential therapeutic interventions. Invasive methods using implanted markers at discrete material points in the myocardium to depict local myocardial deformation that are suitable for use in experimental models have long been available for cardiovascular investigation [1,2]. Such methods include pulse transit time recordings between pairs or arrays of so-nomicrometry crystals as well as cineangiographic imaging of arrays of tantalum markers. However, such methods are too invasive to be used commonly in man, although a few studies in patients undergoing cardiac surgery, particularly cardiac transplantation, have been performed [3]. For research in humans and for clinical applications, many cardiac imaging methods now permit projection, tomographic or 3D assessment of cardiac chamber, epicardial, endocardial and valvular motion. These include roentgenographic contrast ventriculography, transthoracic or transesophageal echocardiography, electron beam CT with intravenous contrast injection, radionuclide SPECT and PET and conventional magnetic resonance (MR) imaging. However, the heart translates through and rotates within any imaging plane during the cardiac cycle.

Keywords

Magn Reson Image Constrictive Pericarditis Transmural Gradient Left Ventricular Deformation Circumferential Segment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • Nathaniel Reichek
    • 1
  1. 1.Research and Education Foundation, DeMatteis CenterSt. Francis HospitalRoslynUSA

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