Abstract
It is well documented that almitrine increases alveolar ventilation through a peripheral chemoreceptor stimulation. Indeed, peripheral chemoreptor denervation in rats (Dhillon, 1980), in cats (Majcherczyk et al., 1984) and dogs (Laubie et al., 1972, 1980) abolished the effects of the drug. Bilateral destruction of the nucleus tractus solitarius in dogs, also abolished the effects of almitrine.
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© 1987 J.A. Ribeiro and David J. Pallot
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Laubie, M., Evrard, Y. (1987). Almitrine Antagonizes the Depressant Effect of the Morphinomimetic Agent, Fentanyl on Bulbar Respiratory Neurons. In: Ribeiro, J.A., Pallot, D.J. (eds) Chemoreceptors in Respiratory Control. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-1155-1_41
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DOI: https://doi.org/10.1007/978-94-015-1155-1_41
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