Abstract
With any pharmaceutical preparation, the control of quality is important for ensuring reliable performance when that preparation is administered to a patient. Conventionally, radiopharmaceutical agents are products in which a radionuclide label is formulated in such a way as to cause it to localise in some organ or lesion. Once localised, the externally detectable radiation may be displayed to produce clinically useful diagnostic information, and radiation which is absorbed may in some cases provide therapeutic benefit. Control of quality of this type of preparation is, in general, aimed at ensuring that a known quantity of the desired radionuclide in the correct chemical combination is administered in a suitable vehicle (one which is sterile and apyrogenic, since in the majority of cases such materials are given by intravenous injection).
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© 1982 C.G. Wilson, J.G. Hardy, M. Frier and S.S. Davis
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Frier, M. (1982). Quality Control of Radiopharmaceuticals. In: Wilson, C.G., Hardy, J.G., Frier, M., Davis, S.S. (eds) Radionuclide Imaging in Drug Research. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-9728-1_6
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DOI: https://doi.org/10.1007/978-94-011-9728-1_6
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-011-9730-4
Online ISBN: 978-94-011-9728-1
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