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Nerve Growth Factor

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Brain

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Abstract

Growth and differentiation of both the sensory and motor components of the peripheral nervous system (PNS) is favored by factors released from peripheral tissues and heterotransplant experiments have established that these effects are not species restricted. Similarly an intact innervation and the release of “supporting factors” from nerve endings are essential for normal development of the periphery and, at least in lower forms, for regeneration following injuries such as limb amputation. The chemical basis for neuron-target and target-neuron interactions within the central nervous system (CNS) has only begun to be explored, but evidence for factors which specifically and selectively influence growth and differentiation of both neural and glial elements has begun to accumulate.

This work was supported by grant #CA-21043-01 from the National Cancer Institute, National Institutes of Health.

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Authors
  1. Barry G. W. Arnason
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  2. Michael Young
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Samuel R. Berenberg M.D.

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© 1977 Martinus Nijhoff, The Hague, Netherlands

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Arnason, B.G.W., Young, M. (1977). Nerve Growth Factor. In: Berenberg, S.R. (eds) Brain. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-8884-5_13

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  • DOI: https://doi.org/10.1007/978-94-011-8884-5_13

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