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Brain pp 184-212 | Cite as

Nerve Growth Factor

  • Barry G. W. Arnason
  • Michael Young

Abstract

Growth and differentiation of both the sensory and motor components of the peripheral nervous system (PNS) is favored by factors released from peripheral tissues and heterotransplant experiments have established that these effects are not species restricted. Similarly an intact innervation and the release of “supporting factors” from nerve endings are essential for normal development of the periphery and, at least in lower forms, for regeneration following injuries such as limb amputation. The chemical basis for neuron-target and target-neuron interactions within the central nervous system (CNS) has only begun to be explored, but evidence for factors which specifically and selectively influence growth and differentiation of both neural and glial elements has begun to accumulate.

Keywords

Nerve Growth Factor Chick Embryo Sympathetic Neuron Sympathetic Ganglion Neurite Extension 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff, The Hague, Netherlands 1977

Authors and Affiliations

  • Barry G. W. Arnason
  • Michael Young

There are no affiliations available

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