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Abstract

Epidemiologie studies of the non-Hodgkin’s lymphomas as one entity, while perhaps a useful first step, have obvious limitations. This is particularly true with regard to attempts to identify aetiologic factors. Clearly there are sufficient differences between reticulum cell sarcoma, lymphosarcoma and Hodgkin’s disease to warrant viewing them separately at present. In contrast to Hodgkin’s disease, lymphosarcoma and reticulum cell sarcoma are rarely localised (Rosenberg and Kaplar, 1970) have unpredictable patterns of spread and frequently involve tonsillar tissue and extra nodal sites, including the bone marrow and liver (Peters et al., 1968). This latter observation is particularly true of reticulum cell sarcoma. There is a high frequency of gastrointestinal tract involvement in the non-Hodgkin’s lymphomas of childhood, and the pattern of spread in Hodgkin’s disease seems to be contiguous whereas in these other lymphomas it is non-contiguous. Other important differences relate to complications and response to therapy. Lymphosarcoma is frequently associated with a lymphatic leukaemia stage. This occurs with less frequency with reticulum cell sarcoma and is rare in Hodgkin’s disease (Beutler, 1954; Rosenberg et al., 1961). Nitrogen mustard appears to be more effective in Hodgkin’s disease than with the other lymphomas, which are in general more resistant to therapy (Livingston and Carter, 1970).

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© 1975 N. J. Vianna

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Vianna, N.J. (1975). Other lymphomas. In: Lymphoreticular Malignancies. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-8053-5_4

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  • DOI: https://doi.org/10.1007/978-94-011-8053-5_4

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