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Prolactin and Prolactin Receptors in Tumor Development, Growth and Cellular Functions

  • Chapter
Hormonal Regulation of Mammary Tumors

Abstract

The importance of prolactin (PRL) in the development and growth of the mammary gland and experimental mammary tumors is clearly established. Prolactin, however, does not act alone in its stimulatory action on normal mammary development nor in its role as an initiator or co-inducer of mammary tumors. A number of other hormones such as estrogens, progesterone, glucocorticoids, thyroid hormones, insulin and growth hormone have been shown to be important for full development and action of the mammary gland (21) and are undoubtedly of great importance in the evolution and maintenance of mammary tumors.

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Authors
  1. Paul A. Kelly
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  2. Jean Djiane
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  3. Philippe Gandilhon
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  4. Alzira A. M. Rosa
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  5. Rene St-Arnaud
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Editors and Affiliations

  1. University of Minnesota, Minneapolis, Minnesota, USA

    Benjamin S. Leung Ph.D. (Associate Professor of Obstetrics and Gynecology, and Director for Reproductive Endocrinology/Oncology Research) (Associate Professor of Obstetrics and Gynecology, and Director for Reproductive Endocrinology/Oncology Research)

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© 1982 Eden Press Inc.

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Kelly, P.A., Djiane, J., Gandilhon, P., Rosa, A.A.M., St-Arnaud, R. (1982). Prolactin and Prolactin Receptors in Tumor Development, Growth and Cellular Functions. In: Leung, B.S. (eds) Hormonal Regulation of Mammary Tumors. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-8045-0_2

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  • DOI: https://doi.org/10.1007/978-94-011-8045-0_2

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-8047-4

  • Online ISBN: 978-94-011-8045-0

  • eBook Packages: Springer Book Archive

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