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Retrovirus Receptors and their Genetics

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Part of the book series: Receptors and Recognition ((RERE,volume 7))

Abstract

Retroviruses are enveloped viruses that occur in numerous vertebrate host species. In order to initiate infection, a specific interaction takes place between viral envelope glycoproteins (the VAPs) and cellular receptor sites (CRS) on the cell surface. While the VAPs have recently been extensively analysed, the biochemical nature of the CRS is not known and the molecular events of viral reception are poorly understood. The genetics of CRS, however, have been elucidated in several species and it is evident that complex polymorphisms of VAP—CRS interactions exist in which retroviruses exhibit a high degree of host–range specificity and, in some cases, tissue tropism.

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© 1981 Chapman and Hall

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Weiss, R.A. (1981). Retrovirus Receptors and their Genetics. In: Lonberg-Holm, K., Philipson, L. (eds) Virus Receptors. Receptors and Recognition, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-8022-1_10

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  • DOI: https://doi.org/10.1007/978-94-011-8022-1_10

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-8024-5

  • Online ISBN: 978-94-011-8022-1

  • eBook Packages: Springer Book Archive

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