Abstract
Of the five polymyxins, A, B, C, D and E, originally isolated from a spore-bearing bacillus called variously B. aerosporus and B. polymyxa (Garrod et al., 1973), only two have found clinical usefulness, namely polymyxin B, usually in the form of the sulphate, and polymyxin E (colistin), either as the sulphate or sodium sulphomethate. They are basic polypeptides which are soluble in water and methanol and fairly heat stable.
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References
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© 1978 ADIS Press
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Ball, A.P., Gray, J.A., Murdoch, J.M. (1978). Peptide Antibiotics (Polymyxin B and Polymyxin E). In: Antibacterial Drugs Today. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-8004-7_14
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DOI: https://doi.org/10.1007/978-94-011-8004-7_14
Publisher Name: Springer, Dordrecht
Print ISBN: 978-0-85200-505-7
Online ISBN: 978-94-011-8004-7
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