Abstract
The circulation of blood serves three vital functions — transport, communication and defence. The interdependence and high metabolic activity of tissues requires that this circulation be rapid and in the closed circulatory system high velocity is achieved as a result of high pressure. Such a high pressure system is especially vulnerable to leakage and it is essential that bleeding due to injured blood vessels is arrested rapidly. The process of haemostasis, which is the spontaneous arrest of blood loss from ruptured vessels, ensures that this occurs. Haemostasis is followed by wound healing.
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Further Reading
Bailey, J.M. (1979) ‘Prostacyclins, Thromboxanes and Cardiovascular Disease’, Trends in Biochemical Sciences, 4, 68–71
Gaffney, P.J. (1981) ‘Thrombosis: A Molecular Approach to Therapy’, Nature, 290, 445–6
Heinmark, R.L., Kurachi, K., Fujikawa, K. and Davie, E.W. (1980) ‘Surface Activation of Blood Coagulation, Fibrinolysis and Kinin Formation’, Nature, 286, 456–60
Jackson, C.M. and Nemenson, Y. (1980) ‘Blood Coagulation’, Annual Reviews of Biochemistry, 49, 765–811
Mustard, J.F., Kinlough-Rathbone, R.L. and Packham, M.A. (1980) ‘Prostaglandins and Platelets’, Annual Review of Medicine, 31, 89–96
Râkóczi, I., Wiman, B. and Conan, D. (1978) ‘On the Biological Significance of the Specific Interaction between Fibrin, Plasminogen and Antiplasmin’, Biochimica et Biophysica Acta, 540, 295–300
Zucker, M.B. (1980) ‘The Functioning of Blood Platelets’, Scientific American, 242, 70–89
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© 1982 N.J. Russell, G.M. Powell, J.G. Jones, P.J. Winterburn and J.M. Basford
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Russell, N.J., Powell, G.M., Jones, J.G., Winterburn, P.J., Basford, J.M. (1982). Haemostasis. In: Blood Biochemistry. Croom Helm Biology in Medicine Series. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7892-1_9
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DOI: https://doi.org/10.1007/978-94-011-7892-1_9
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-011-7894-5
Online ISBN: 978-94-011-7892-1
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