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Proceedings of the First International Conference on Interfaces in Medicine and Mechanics pp 69–77Cite as

Changes in the Material Properties and Function of Pericardial Bioprosthetic Heart Valves Invivo

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Summary

We have studied changes in the function and material properties of pericardial heart valves which had been implanted for between 2 and 7 years and were free from calcification and leaflet tears when explanted. Similar measurements have also been made on the characteristics of pericardial valves which have been cycled in laboratory fatigue tests for 400 million cycles. Explanted valves had restricted leaflet opening and increased pressure differences during forward flow. Fibrous tissue ingrowth, leaflet thickening and reduced tissue extensibility contributed to the change in valve function. Little change was seen in the function of valves after laboratory fatigue tests although there was a significant reduction in tissue extensibility.

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References

  1. IONESCU, C.I., TANDON, A.P., SILVERTON, N.P. et al., Biological and Bioprosthetic Valves, Ed by Bodnar, E. Yacoub, M. New York, Yorke Medical Books, 1986, pp. 165–176.

    Google Scholar 

  2. FISHER, J., REECE, I.J., WHEATLEY, D.J., Thoracic and Cardiovasc Surgeon, 1986, 34, 157.

    Article  Google Scholar 

  3. COSGROVE, D.M., LYTLE, B.N., GILL, G.C. et al., J. Thorac Cardiovasc. Surg. 1985, 89, 358.

    Google Scholar 

  4. WHEATLEY, D.J., FISHER, J., REECE, I.J. et al. Primary tissue failure in pericardial heart valves. J. Thorac Cardiovasc. Surg. 1987, 94, 367.

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  5. IONESCU, M.I. Biological and Bioprosthetic valves, Ed. by Bodnar, E. Yacoubs, M., New York, Yorke Medical Brooks, pp. 77–79.

    Google Scholar 

  6. FISHER, J., WHEATLEY, D.J. Eur. J. Cardiothorcic Surg. 1987, 1, 71.

    Article  Google Scholar 

  7. LAWFORD, P.V., BLACK, M.M., DRURY, P.J. et al. Eng. in Med. 1987, 16, 95.

    Article  Google Scholar 

  8. SCHOEN, F.J., J. Biomed. Mat. Res. 1987, 21, 117.

    Google Scholar 

  9. THUBRIKAR, M.J., DECK, D.T., AOUAD, J., NOLAN, S.P., J. Thorac. Cardiovasc. Surg., 1983, 86, 115.

    Google Scholar 

  10. FISHER, J., JACK, G.R., WHEATLEY, D.J., Clin. Phys. and Physiol. Meas. 1986, 7, 63.

    Article  Google Scholar 

  11. GHISTA, D.N., Med. Biol. Eng. Coroput. 1976, 5, 122.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Dept. of Mechanical Engineering, University of Leeds, UK

    J. Fisher

  2. Bioengineering Unit, University of Strathclyde, UK

    P. Zioupos & J. C. Barbenel

  3. Dept. of Cardiac Surgery, Glasgow University, UK

    D. J. Wheatley

Authors
  1. J. Fisher
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  2. P. Zioupos
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  3. J. C. Barbenel
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  4. D. J. Wheatley
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Editor information

Editors and Affiliations

  1. Department of Basic Dental Science, University of Wales College of Medicine, UK

    K. R. Williams

  2. ENT Department, University Hospital of Wales, UK

    T. H. J. Lesser

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© 1989 Biomaterials Research Group

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Cite this paper

Fisher, J., Zioupos, P., Barbenel, J.C., Wheatley, D.J. (1989). Changes in the Material Properties and Function of Pericardial Bioprosthetic Heart Valves Invivo. In: Williams, K.R., Lesser, T.H.J. (eds) Proceedings of the First International Conference on Interfaces in Medicine and Mechanics. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7477-0_6

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  • DOI: https://doi.org/10.1007/978-94-011-7477-0_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-7479-4

  • Online ISBN: 978-94-011-7477-0

  • eBook Packages: Springer Book Archive

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