Abstract
Among the various forms constituting the spectrum of headache disorders cluster headache (CH) certainly is the most peculiar and represents an interesting model of dysrhythmic condition involving nociception, endocrine and autonomic symptoms. The most common variety of the disease, episodic CH, displays a circannual pattern similar to peptic ulcer and cyclic depression, but also in the chronic type the typical circadian and ultradian occurrence of the attacks is observable (1, 2). The pathogenesis of CH is still unknown and an involvement of CNS has been proposed, based on the alterations found in several rhythmic biological functions as well as on the effects of some drugs and procedures able to interfere with the course of periodic disorders of central origin (3, 4, 5).
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Savoldi, F., Bono, G., Manzoni, G.C., Micieli, G., Lanfranchi, M., Nappi, G. (1984). Lithium and rubidium compounds in cluster headache: overview and perspectives. In: Corsini, G.U. (eds) Current Trends in Lithium and Rubidium Therapy. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7318-6_24
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DOI: https://doi.org/10.1007/978-94-011-7318-6_24
Publisher Name: Springer, Dordrecht
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