Abstract
In 1976 during the First International Congress on the Menopause, I (Larsson-Cohn) had the pleasure of chairing a workshop with a title similar to that of the present one. On that occasion it became clear that until the mid-seventies very little investigative work had been done on the metabolic consequences of post-menopausal hormone replacement therapy. Some studies had been performed in connection with the effects of combined oral contraceptive agents, but it was difficult to extrapolate from these the effects of oestrogens per se, and those of progestogens. The problem was further complicated by the fact that at that time it was not unusual for authors to state merely that the women in their studies had been taking ‘oral contraceptives’, without specifying the composition of the preparations taken. In other instances the results from subjects taking different oral contraceptive agents were pooled.
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References
Gordon, T., Castelli, W. P., Hjortland, M. C. and Kannel, W. B. (1977). The prediction of coronary heart disease by high-density and other lipoproteins; an historical perspective. In Rifkind, B. M. and Levy, R. I. (eds.) Hyperlipidemia, p. 71. ( New York: Grune and Stratton )
Hammond, C. B., Jelovsek, F. R., Lee, K. L., Creasman, W. T. and Parker, R. T. (1979). Effects of long-term estrogen replacement therapy. I. Metabolic effects. Am. J. Obstet. Gynecol., 133, 525
Hirvonen, E., Mälkönen, M. and Manninen, V. (1981). Effects of different progestogens on lipoproteins during postmenopausal replacement therapy. N. Engl. J. Med., 304, 5600
Johansson, M. W., Kaij, L., Kullander, S., Lennér, H.-C., Svanberg, L. and Astedt, B. (1975). On some late effects of bilateral oophorectomy in the age range 15–30 years. Acta Obstet. Gynecol. Scand., 54, 499
Larsson-Cohn, U., Fâhraeus, L., Wallentin, L. and Zador, G. (1981). Lipoprotein changes may be minimized by proper composition of a combined oral contraceptive. Fertil. Steril., 35, 172
Rosenberg, L., Hennekens, C. H., Rosner, B., Belander, C., Rothman, K. J. and Spizer, F. E. (1981). Early menopause and the risk of myocardial infarction. Am. J. Obstet. Gynecol., 139, 47
Ross, R. K., Paganini-Hill, A., Mack, T. M., Arthur, M. and Henderson, B. E. (1981). Menopausal oestrogen therapy and protection from death from ischaemic heart disease. Lancet, 1, 858
Steinberg, D. (1978). The rediscovery of high density lipoprotein; a negative risk factor in atherosclerosis. Eur. J. Clin. Invest., 8, 107
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van Keep, P.A., Utian, W.H., Vermeulen, A. (1982). Some biochemical consequences of post-menopausal hormone replacement treatment. In: van Keep, P.A., Utian, W.H., Vermeulen, A. (eds) The Controversial Climacteric. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7253-0_4
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DOI: https://doi.org/10.1007/978-94-011-7253-0_4
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