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Progestogen Modification of Estrogen-induced Endometrial Proliferation in Climacteric Women

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The Menopause and Postmenopause

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Abstract

Few topics provoke more discussion than the relationship between exogenous estrogens and endometrial carcinoma, and the recent publication in America of retrospective studies reporting an increase in the risk ratio for cancer following prolonged estrogen therapy1–6 has further fuelled this controversy. The statistical, clinical and pathological biases and inadequacies of this type of investigation have been discussed extensively7–11, but it is highly unlikely that the reported relationship is spurious12.

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Authors
  1. M. I. Whitehead
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  2. J. McQueen
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  3. J. Minardi
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  4. S. Campbell
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Editor information

Editors and Affiliations

  1. Cattedra di Patologia Ostetrica e Ginecologica, Univeristà di Roma, V. le Regina Elena, 324-00161, Roma, Italy

    N. Pasetto

  2. Istituto di Farmacologia, Università di Milano, Via Vanvitelli, 32-Milano, Italy

    R. Paoletti

  3. Department of Health, State of New York, Roswell Park Memorial Institute, 14263, Buffalo, New York, USA

    J. L. Ambrus

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© 1980 MTP Press Limited

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Whitehead, M.I., McQueen, J., Minardi, J., Campbell, S. (1980). Progestogen Modification of Estrogen-induced Endometrial Proliferation in Climacteric Women. In: Pasetto, N., Paoletti, R., Ambrus, J.L. (eds) The Menopause and Postmenopause. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7230-1_4

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  • DOI: https://doi.org/10.1007/978-94-011-7230-1_4

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-7232-5

  • Online ISBN: 978-94-011-7230-1

  • eBook Packages: Springer Book Archive

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