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The Effects of Exogenous Estrogen Replacement on Breast Parenchymal Patterns

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The Menopause and Postmenopause

Abstract

Mammary ducts and lobules are subject to the physiological influence of pituitary, adrenal and ovarian hormones. The association of these hormones as well as exogenous steroids with breast maturation and neoplasia is complex and the subject of great debater1–10.

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References

  1. Gullino, P. M. (1977). Natural history of breast cancer. Progression from hyperplasia to neoplasia as predicted by angiogenesis. Cancer, 39 (6 Suppl.), 2697

    Article  PubMed  CAS  Google Scholar 

  2. Humphrey, L. J. and Swerdlow, M. (1962). Relationship of benign breast disease to carcinoma of the breast. Surgery, 52, 841

    PubMed  CAS  Google Scholar 

  3. Kodlin, D., Winger, E. E. and Morgenstern, N. L. et al. (1977). Chronic mastopathy and bréast cancer. A follow-up study. Cancer, 39, 2603

    Article  PubMed  CAS  Google Scholar 

  4. Krook, P. M., Carlile, T., Bush, W. and Hall, M. (1978)’ Mammographie parenchymal patterns as a risk indicator for prevalent and incident cancer. Cancer, 41, 1093

    Article  PubMed  CAS  Google Scholar 

  5. Leis, H. P. Jr. (1976). Hormones in the epidemiology of breast cancer. Breast - Dis. Breast, 2, 7

    CAS  Google Scholar 

  6. Lipsett, M. D. (1977). Estrogens use and cancer risk. J. Am. Med. Assoc., 237, 1112

    Article  CAS  Google Scholar 

  7. Lipschutz, A. and Varga, L. Jr. (1940). Tumorgenic powers of stilbestrol and follicular hormone. Lancet, 1, 541

    Article  Google Scholar 

  8. Muir, R. (1941). The evolution of carcinoma of the mamma. J. Pathol. Bacteriol., 52, 155

    Article  CAS  Google Scholar 

  9. Suteri, P. (1974). Endocrine aspects of breast cancer. In J. R. Castro, T. S. Meyler and D. G. Baker (eds.). Current Concepts in Breast Cancer. ( Flushing: Medical Examination Publishing Co. Inc. )

    Google Scholar 

  10. Wallace, R. B., Sherman, B. M., Bean, J. A. and Leeper, J. (1978). Thyroid hormone use in patients with breast cancer: absence of an association. J. Am. Med. Assoc., 239, 958

    Article  CAS  Google Scholar 

  11. Black, M. M., Barclay, T. H. and Cutler, S. J. et al. (1972). Association of atypical characteristics of benign breast lesions with subsequent risk of breast cancer. Cancer, 29, 339

    Google Scholar 

  12. Black, M. D. and Leis, H. P. Jr. (1972). Mammary carcinogenesis: influence of parity and estrogens. N.Y. State J. Med., 72, 1601

    PubMed  CAS  Google Scholar 

  13. Carter, D. (1977). Intraductal papillary tumors of the breast. A study of 78 cases. Cancer, 39, 1689

    Article  PubMed  CAS  Google Scholar 

  14. Cheatle, G. L. (1926). Desquamative and dysgenetic epithelial hyperplasia in breast: their situation and characteristics: their likeness to lesions induced by tar. Br. J. Surg., 13, 509

    Article  Google Scholar 

  15. Dao, T. L. (1972). The question of `preneoplastic’ lesions. J. Surg. Oncol., 4, 397

    Article  PubMed  CAS  Google Scholar 

  16. Dawson, E. K. (1933). Carcinoma in mammary lobule and its origin. Edinburgh Med. J., 40, 57

    Google Scholar 

  17. Fisher, E. R., Shoemaker, R. H. and Sabnis, A. (1975). Relationship of hyperplasia to cancer in 3-methylocholanthrene-induced mammary tumorgenesis. Lab. Invest., 33, 33

    Google Scholar 

  18. Jensen, H. M., Rice, J. R. and Wellings, S. R. (1976). Preneoplastic lesions in the human breast. Science, 191, 295

    Article  PubMed  CAS  Google Scholar 

  19. Kern, W. H. and Brooks, R. N. (1969). A typical epithelial hyperplasia associated with breast cancer and fibrocystic disease. Cancer,24, 668

    Article  Google Scholar 

  20. Medina, D. and Warner, M. R. (1976). Mammary tumorgenesis in chemical carcinogen-treated mice. Induction of mammary ductal hyperplasias. J. Natl. Cancer Inst., 57, 57

    Google Scholar 

  21. Moskowitz, M. and Wirman, J. (1976). Proliferative mammary dysplasia with subsequent development of in situ cancer. Breast, 2, 34

    Google Scholar 

  22. Ryan, J. A. and Coady, C. J. (1952). Ductal proliferation in breast cancer. Canad. J. Surg., 5, 12

    Google Scholar 

  23. Sinha, D. and Dao, T. L. (1977). Hyperplastic alveolar nodules of the rat mammary gland: tumor-producing capability in vivo and vitro. Cancer Lett., 2, 153

    Article  CAS  Google Scholar 

  24. Slemmer, G. (1972). Host response to premalignant mammary tissues. Natl. Cancer Inst. Monogr., 35, 57

    PubMed  CAS  Google Scholar 

  25. Wellings, S. R. and Jensen, H. M. (1975). An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J. Natl. Cancer Inst., 55, 231

    PubMed  CAS  Google Scholar 

  26. Welsch, C. W. (1976). Prophylaxis of early preneoplastic lesions of the mammary gland. Cancer Res., 36, 2621

    PubMed  CAS  Google Scholar 

  27. Wolfe, J. N. (1976). Risk of breast cancer development determined by mammographie parenchymal pattern. Cancer, 37, 2486

    Article  PubMed  CAS  Google Scholar 

  28. Wolfe, J. N. (1976). Breast patterns as an index of risk for developing cancer. Am. J. Roentgenol., 126, 1130

    CAS  Google Scholar 

  29. Wellings, S. R. and Wolfe, J. N. (1978). Correlative studies of the histological and radiographic appearance of the breast parenchyma. Radiology, 129, 299

    PubMed  CAS  Google Scholar 

  30. Anderson, I., Andren, L. and Petterson, H. (1978). Influence of age at first pregnancy on breast parenchymal pattern: a preliminary report. Radiology, 126, 675

    Google Scholar 

  31. Ernster, V. L., Sacks, S. T. and Peterson, C. (1979). Mammographic parenchymal patterns and risk factors for breast cancer. Paper presented to the Third Annual Meeting of the American Society for Preventive Oncology, New York, March 8–9

    Google Scholar 

  32. Wilkinson, E., Clopton, C., Gordonson, J., Green, R., Hill, A. and Pike, M. C. (1978). Mammographic parenchymal pattern and the risk of breast cancer. Am. J. Roentgenol., 130, 1157

    Google Scholar 

  33. Peck, D. P. and Lowman, R. M. (1978). Estrogen and the postmenopausal breast: mammographic considerations. J. Am. Med. Assoc., 240, 1733

    Article  CAS  Google Scholar 

  34. Casagrande, J., Gerkins, V., Henderson, B. E., Mack, T. and Pike, M. C. (1976). Exogenous estrogens and breast cancer in women with natural menopause. J. Natl. Cancer Inst., 56, 839

    PubMed  CAS  Google Scholar 

  35. Hoover, R., Gray, L. A. Sr., Cole, P. and MacMahon, B. (1976). Menopausal estrogens and breast cancer. N. Engl. J. Med., 295, 401

    Article  PubMed  CAS  Google Scholar 

  36. Thomas, D. B. (1978). Role of exogenous female hormones in altering the risk of benign and malignant neoplasms in humans. Cancer Res., 38, 3991

    PubMed  CAS  Google Scholar 

  37. Hainline, S., Myers, L., McLelland, R., Newell, J., Grufferman, S. and Shingleton, W. (1978). Mammographic patterns and risk of breast cancer. Am. J. Roentgenol., 130, 1157

    CAS  Google Scholar 

  38. Mendell, L., Rosenbloom, M. and Naimark, A. (1977). Are breast patterns a risk index for breast cancer? A reappraisal. Am. J. Roentgenol., 128, 547

    CAS  Google Scholar 

  39. Peyster, R. G., Kalisher, L. and Cole, P. (1977). Mammographie parenchymal patterns and prevalence of breast cancer. Radiology, 125, 387

    PubMed  CAS  Google Scholar 

  40. Egan, R. L. (1979). Estimated risk and occurrence of breast cancer in asymptomatic and minimally symptomatic patients. Cancer, 43, 871

    Article  PubMed  CAS  Google Scholar 

  41. Foote, F. W. and Stewart, F. W. (1945). Comparative studies of cancerous versus noncancerous breasts. Ann. Surg., 121, 6, 197

    Article  PubMed  CAS  Google Scholar 

  42. Hertz, R. (1976). The estrogen-cancer hypothesis. Cancer, 38, 534

    Article  PubMed  CAS  Google Scholar 

  43. Kapdi, C. C. and Wolfe, J. N. (1976). Breast cancer: relationship to thyroid supplements for hypothyroidism. J. Am. Med. Assoc., 236, 1124

    Article  CAS  Google Scholar 

  44. Mustacchi, P. and Greenspan, R. (1977). Thyroid supplementation of hypothyroidism: an iatrogenic cause of breast cancer? J. Am. Med. Assoc., 237, 1446

    Article  CAS  Google Scholar 

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Authors
  1. J. B. Buchanan
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  2. K. I. Bland
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  3. B. F. Weisberg
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  4. L. A. Gray Sr.
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Editor information

Editors and Affiliations

  1. Cattedra di Patologia Ostetrica e Ginecologica, Univeristà di Roma, V. le Regina Elena, 324-00161, Roma, Italy

    N. Pasetto

  2. Istituto di Farmacologia, Università di Milano, Via Vanvitelli, 32-Milano, Italy

    R. Paoletti

  3. Department of Health, State of New York, Roswell Park Memorial Institute, 14263, Buffalo, New York, USA

    J. L. Ambrus

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© 1980 MTP Press Limited

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Buchanan, J.B., Bland, K.I., Weisberg, B.F., Gray, L.A. (1980). The Effects of Exogenous Estrogen Replacement on Breast Parenchymal Patterns. In: Pasetto, N., Paoletti, R., Ambrus, J.L. (eds) The Menopause and Postmenopause. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7230-1_25

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  • DOI: https://doi.org/10.1007/978-94-011-7230-1_25

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-7232-5

  • Online ISBN: 978-94-011-7230-1

  • eBook Packages: Springer Book Archive

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