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Interaction of Phages with their Receptor Proteins

  • Chapter
Virus Receptors

Part of the book series: Receptors and Recognition ((RERE))

Abstract

Although biologists have been fascinated by phage adsorption for almost half a century, they haven’t been able to solve all its mysteries. The basis for the extremely high efficiency of phage adsorption, discussed by Schlesinger [177] is still a matter of controversy [184, 17]. The identification of the chemical determinants recognized by the phage at the bacterial surface, the receptors, first attempted by Weidel and his colleagues [222, 223, 224, 234] still represents one of the most active areas of research in microbiology [117, and Chapters 2, 3 and 4]. The protein of the phage responsible for the interaction with the receptor, the ‘adsorption protein’, has rarely been identified with certainty. Nevertheless I shall try to show in this review that one can begin to think in molecular terms about phage adsorption and phage — receptor interaction.

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Schwartz, M. (1980). Interaction of Phages with their Receptor Proteins. In: Randall, L.L., Philipson, L. (eds) Virus Receptors. Receptors and Recognition. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6918-9_4

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