Abstract
Since the mid 1980’s, the field of metal ion chemistry has rapidly expanded to include the molecular biologists intrigued by the involvement of heavy metals in gene function and regulation. In particular, metals such as copper that are both toxic and essential for life represent an interesting dichotomy to metal ion biologists; much research currently focuses on identifying the cellular factors controlling accumulation, distribution and detoxification of these ions. The bakers yeast S. cerevisiae provides an ideal system in which to conduct these studies. The application of yeast molecular genetics should facilitate the isolation of key genes controlling metal ion homeostasis and should provide the molecular tools for probing structure and function of the encoded proteins.
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© 1993 Chapman & Hall, Inc.
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Culotta, V.C., Lapinskas, P., Liu, X.F. (1993). Mechanisms of Copper Ion Homeostasis in Yeast. In: Karlin, K.D., Tyeklár, Z. (eds) Bioinorganic Chemistry of Copper. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6875-5_10
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DOI: https://doi.org/10.1007/978-94-011-6875-5_10
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