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Abstract

Nutritional anemias are usually gratifying to diagnose and to treat from the point of view of the patient as well as the physician. If the diagnosis is correct the patient will, in most cases, respond quickly and completely to inexpensive and harmless medication. If it were not for the fact that a number of fairly common problems masquerade as nutritional anemias and do not respond to the therapy, this discussion on diagnosis could be abbreviated.

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References

  1. ALFREY, C.P., and LANE, M. 1970. The effect of riboflavin deficiency on erythropoiesis. Semin. Hematol. 3:49.

    Google Scholar 

  2. BRISE, H. and HALBERG, L. 1962. Iron absorption studies II. Ab- sorbabihty of different iron compounds. Acta. Medica Scandinavica, 171, supplement 376.

    Google Scholar 

  3. BRISE, H. 1962. Iron absorption studies II. Influence of meals on iron absorption in oral iron therapy. Acta. Medica Scandinavica, 171, supplement 376.

    Google Scholar 

  4. BRUNSER, O., REID, A., MONCKEBERG, F., MACCIONI, A., and CONTRERAS, I. 1968. Jejunal mucosa in infant malnutrition. Am. J. Clin. Nutr. 21:876.

    Google Scholar 

  5. BUTTERWORTH, C.E., and KRUMDIECK, C.L. 1975. Intestinal absorption of fohc acid monoglutamates and polyglutamates: A brief review of some recent developments. Br. J. Haematol. 31, supplement 111.

    Article  Google Scholar 

  6. CALLENDER, S.T. 1969. Quick and slow-release iron: a double-blind trial with a single daily dose regimen. British Medical Journal, 4, 531.

    Article  CAS  Google Scholar 

  7. CHANARIN, I. 1969. The Megaloblastic Anaemias. Davis, Philadelphia.

    Google Scholar 

  8. CHANARIN, I. 1976. Investigation and management of megaloblastic anemia. Clin. Haematol. 5:747.

    Google Scholar 

  9. CHANARIN, L, ENGLAND, J.M., and HOFFBRAND, A.V. 1973. Significance of large red blood cells. Br. J. Haematol. 25:351.

    Article  CAS  Google Scholar 

  10. CHUNG, A.S., PEARSON, W.N., DARBY, W.J., MILLER, O.N., and GOLDSMITH, GA. 1961. Folic acid, vitamin Bg, pantothenic acid, and vitamin B12 in human dietaries. Am. J. Clin. Nutr. 8:573.

    Google Scholar 

  11. COLMAN, N., BARKER, E.A., BARKER, M., GREEN, R., and METZ, J. 1975A. Prevention of folate deficiency by food fortification. IV. Identification of target groups in addition to pregnant females in an adult rural population. Am. J. Clin. Nutr. 28:471.

    CAS  Google Scholar 

  12. COLMAN, N., GREEN, R., and METZ, J. 1975B. Prevention of folate deficiency by food fortification. II. Absorption of folic acid from fortified staple foods. Am. J. Clin. Nutr. 28:459.

    CAS  Google Scholar 

  13. COOPER, B.A., and WHITEHEAD, V.M. 1978. Evidence that some patients with pernicious anemia are not recognized by radiodilution assay for cobalamin in serum. N. Engl. J. Med. 299:816.

    Article  CAS  Google Scholar 

  14. CORDANO, A., PLACKO, R.P., and GRAHAM, G.G. 1966. Hypocu- premia and neutropenia in copper deficiency. Blood 28:280.

    CAS  Google Scholar 

  15. CROFT, R.F., STREETER, A.M., and O’NEILL, B.J. 1974. Red cell indices in megaloblastosis and iron deficiency. Pathology 6:107.

    Article  CAS  Google Scholar 

  16. DAS, K.C., and HERBERT, V. 1976B. Vitamin B12 folate interrelations. Clin. Haematol. 5:697.

    CAS  Google Scholar 

  17. ELWOOD, P.C., and WILLIAMS, G. 1970. A comparative trial of slow- release and conventional iron preparations. Practitioner 204:812.

    CAS  Google Scholar 

  18. ENGLAND, J.M., WALFORD, D.M., and WATERS, D.A.W. 1972. Reassessment of the rehabihty of the hematocrit. Br. J. Haematol. 23:247.

    Article  CAS  Google Scholar 

  19. FINCH, C.A. 1975. Erythropoiesis in protein-calorie malnutrition, in Protein-Calorie Malnutrition. (R.E. Olson, ed.) pp 247. Academic Press, New York.

    Google Scholar 

  20. GARBY, L. and AREEKUL, S. 1973. Fish-sauce as a vehicle for iron supplementation in Thailand. A study of its production and consumption, effects of addition of iron salts, absorption of iron from enriched meals and effect on the packed red cell volume values of one year’s consumption of enriched fish-sauce in a Thai village. To be published.

    Google Scholar 

  21. GERSON, C.D., COHEN, N., HEPNER, G.W., BROWN, N., HERBERT, v., and JANOWITZ, H.D. 1971. Folic acid absorption in man: Enhancing effect of glucose. Gastroenterology 61:224.

    CAS  Google Scholar 

  22. HEINIVAARA, O., and PALVA, LP. 1964. Malabsorption of vitamin Bi2 during treatment with p-aminosalicylic acid. Acta. Med. Scandinavica. 175:469.

    Article  CAS  Google Scholar 

  23. HERBERT, V. 1962. Experimental nutritional folate deficiency in man. Trans. Assoc. Am. Physicians 75:307.

    CAS  Google Scholar 

  24. HERBERT, V. 1963. A palatable diet for producing experimental folate deficiency in man. Am. J. Clin. Nutr. 12:17.

    CAS  Google Scholar 

  25. HERBERT, V. 1975. Megaloblastic anemias, in Textbook of Medicine, 14th ed. (P.B. Beeson and W. McDermott, eds.) pp 1404. Saunders, Philadelphia.

    Google Scholar 

  26. HERBERT, V. 1977. The blood in hypothyroidism, m The Thyroid. (S.C. Werner and S. H. Ingbar, ed.) Harper & Row, New York in press.

    Google Scholar 

  27. HERBERT, V. 1977. Anemias, in Nutritional Disorders of American Women (M. Winick, ed) pp 79, Wiley, New York.

    Google Scholar 

  28. HERBERT, V., and ZALUSKY, R. 1962. Interrelations of vitamin B12 and folate metabolism: Folic acid clearance studies. J. Clin. Invest. 41:1263.

    Article  CAS  Google Scholar 

  29. HERBERT, V., COLMAN, N., SPIVACK, M., OCASIO, E., GHANTA, V., KIMMEL, K., BRENNER, L., FREUNDLICH, J., and SCOTT, J. 1975. Folic acid deficiency in the United States: Folate assays in a prenatal clinic. Am. J, Obstet. Gynecol. 123:175.

    CAS  Google Scholar 

  30. JACOBSON, E.D., CHODOS, R.B., and FALOON, W.W. 1960. An experimental malabsorption syndrome induced by neomycin. Am. J. Med. 28:524.

    Article  CAS  Google Scholar 

  31. KRUMDIECK, C.L., and BAUGH, C.M. 1969. The solid phase synthesis of polyglutamates of folic acid. Biochemistry 8:1568.

    Article  CAS  Google Scholar 

  32. MANZOOR, M., and RUNCIE, J. 1976. Folate-responsive neuropathy: Report of ten cases. Br. Med. J. 1:1176.

    Article  CAS  Google Scholar 

  33. MOLLIN, D.L., BOOTH, C.C., and BAKER, S.J. 1957. The absorption of vitamin B12 in control subjects in Addisonian pernicious anemia and in the malabsorption syndrome. Br. J. Haematol. 3:412.

    Article  CAS  Google Scholar 

  34. REYNOLDS, E.H. 1976. Neurologic aspects of folate and vitamin B12 metabolism. Clin. Haematol. 5:661.

    CAS  Google Scholar 

  35. SAMUELSSON, G., and SJOLIN, S. 1972. An epidemiological study of child health and nutrition in a northern Swedish country. Acta Pediatrica Scandinavica. 61, 63–72.

    Article  Google Scholar 

  36. SILVER, H., and FRANKEL, S. 1971. Normal values for mean cor puscular volume as determined by the Model S Coulter Counter. Am. J Clin. Pathol. 55:438.

    CAS  Google Scholar 

  37. SOLAKANNEL, S.J., PALVA, L.P., and TUKKUNEN, J.T. Malabsorp tion of vitamin B12 during treatment with slow-release potassium chlo ride. Acta Medica Scandinavica. 187:431.

    Google Scholar 

  38. SOOD, S.K., BANERJI, L., and RAMALINGASWAMI, V. 1968. Occur rence of nutritional anemias in tropical countries.In Occurrence, Causes and Prevention of Nutritional Anaemias, ed. Blix, G. Uppsala: Almqvist & Wiksells.

    Google Scholar 

  39. SULLIVAN, L.W., and HERBERT, V. 1965. Studies on the minimum daily requirement for vitamin B12. N. Engl. J. Med. 272:340.

    Article  CAS  Google Scholar 

  40. TAMURA, T., and STOKSTAD, E., L.R. 1973. The availabihty of food folate in man. Br. J. Haematol. 25:513.

    Article  CAS  Google Scholar 

  41. TANDON, B.N., MAGOTRA, M.L., SARAYA, A.K., and RAMALINGA- SWAMI, V. 1968. Small intestine in protein malnutrition. Am. J. Clin. Nutr. 21:813.

    CAS  Google Scholar 

  42. TISMAN, G., and HERBERT, V. 1971. Inhibition by penicillamine of DNA synthesis by human bone marrow in vitro. Fed. Proc. 30:518.

    Google Scholar 

  43. TOSKES, P.P., and DEREN, J.J. 1972. Selective inhibition of vitamin Bi2 absorption by paraaminosahcylic acid. Gastroenterology 62:1232.

    CAS  Google Scholar 

  44. TOSKES, P.P., HANSELL, J., CERDA, J., and DEREN, J.J. 1971. Vitamin B12 malabsorption in chronic pancreatic insufficiency. Studies suggesting the presence of a pancreatic “intrinsic factor.” N. Eng. J. Med. 284:627.

    Article  CAS  Google Scholar 

  45. TOSKES, P.P., DEREN, J.J., and CONRAD, M.E. 1973. Trypsin-like nature of the pancreatic factor that corrects vitamin B12 malabsorption associated with pancreatic dysfunction. J. Clin. Invest. 52:1660.

    Article  CAS  Google Scholar 

  46. VITERI, F.E., ALVARADO, J., LUTHRINGER, D.G., and WOOD, R.P. 1968. Hematological changes in protein calorie malnutrition. Vitamin Horm. 26:573.

    Article  CAS  Google Scholar 

  47. WEBB, D.L, CHODOS, R.B., MAHAR, C.Q., and FALOON, W.W. 1968. Mechanism of vitamin B12 malabsorption in patients receiving colchicine. N. Engl. J. Med., 279:845.

    Article  CAS  Google Scholar 

  48. WHO GROUP OF EXPERTS. 1972. Nutritional Anaemias. WHO Technical Report Ser. #503, Geneva.

    Google Scholar 

  49. WHO SCIENTIFIC GROUP 1968. Nutritional Anaemias. WHO Technical Report Ser. #405, Geneva.

    Google Scholar 

  50. WILLIAMS, M.L.,SHOTT,R.J., O’NEAL, P.L., and OSKI, F. 1975. Role of dietary iron and fat on vitamin E deficiency anemia of infancy. N. Engl. J. Med. 292:887.

    CAS  Google Scholar 

  51. WU, A., CHANARIN, I., SLAVIN,G., and LEVI, A.J. 1975. Folate deficiency in the alcohohc—Its relationship to chnical and haematological abnormahties, liver disease and folate stores. Br. J. Haematol. 29:469.

    Article  Google Scholar 

  52. COMMITTEE ON MATERNAL NUTRITION. 1970. Maternal Nutrition and the Course of Pregnancy, National Academy of Sciences, Washington, D.C.

    Google Scholar 

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Streiff, R.R. (1981). Nutritional Anemias. In: Barness, L.A., Coble, Y.D., MacDonald, D.I., Christakis, G. (eds) Nutrition and Medical Practice. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6695-9_27

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  • DOI: https://doi.org/10.1007/978-94-011-6695-9_27

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-6697-3

  • Online ISBN: 978-94-011-6695-9

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