Abstract
Modern agriculture has become increasingly reliant on the use of antibiotics routinely to maintain good animal performance in intensive rearing systems. The subsequent decline in efficiency and occurrence of disease associated with drug resistance (Smith, 1960) caused a re-evaluation of their use, and the eventual adoption of the recommendations of the Swann Committee Report (1969) was viewed with considerable alarm being estimated to have a potential cost to British Agriculture of approximately Σ30 million per annum. The prospect of equating antibodies rather than antibiotics with animal health is a serious goal for all conservationists and the now universal concern to restrict the use of antibiotics for the more serious health problems makes immunoprophylaxis of animal diseases an urgent objective.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Allen, W. D. and Porter, P. (1973). The relative distribution of IgM and IgA cells in intestinal mucosa and lymphoid tissue of the young pig and their significance in the ontogenesis of secretory immunity. Immunology, 24, 493
Allen, W. D. and Porter, P. (1975). The localization of immunoglobulins in intestinal mucosa and the production of secretory antibodies in response to intraluminal administration of bacterial antigens in the pre-ruminant calf. Clin. Exp. Immunol., 21, 407
Allen, W. D., Smith, C. G. and Porter, P. (1973). Localization of intracellular immunoglobulin A in porcine intestinal mucosa using enzyme labelled antibody. Immunology, 25, 55
Atkins, A. M., Schofield, G. C. and Reeders, T. (1971). Studies on the structure and distribution of IgA containing cells in the gut of the pig. J. Anat., 109, 385
Brandtzaeg, P. (1974). Mucosal and glandular distribution of immunoglobulin components. Immunology, 26, 1101–1114.
Butler, J. E., Kiddy, C. A., Maxwell, C., Hylton, M. B. and Asofsky, R. (1971). Synthesis of immunoglobulins in various tissues of the cow. J. Dairy Sci., 54, 1324
Cebra, J. J. (1969). Immunoglobulins and immunocytes. Bact. Rev., 33, 151
Eidelman, S. and Davies, S. D. (1968). Immunoglobulin content of intestinal mucosal plasma cells in ataxia telangiectasia. Lancet, i, 884
Fréter, R. and Gangarosa, E. J. (1963). Oral Immunization and production of coproantibody in human volunteers. J. Immunol., 91, 724
Lawton, A. R., Asofsky, R., Hylton, M. B. and Cooper, M. D. (1972). Suppression of immunoglobulin synthesis in mice. J. Exp. Med., 135, 277
Mattioli, C. A. and Tomasi, T. B. (1973). The life span of IgA plasma cells from the mouse intestine. J. Exp. Med., 138, 452
Ogra, P. L. and Karzon, D. T. (1969). Distribution of polio virus antibody in serum nasopharynx and alimentary tract following segmental immunization of lower alimentary tract with Polio vaccine. J. Immunol., 102, 1423
Poger, M. E. and Lamm, M. E. (1974). Localization of free and bound secretory component in human intestinal epithelial cells. J. Exp. Med., 139, 629
Porter, P. and Allen, W. D. (1969). Intestinal IgA in the pig. Experientia, 26, 90
Porter, P., Kenworthy, R. and Allen, W. D. (1974). Effect of oral immunization with E. coli antigens on post weaning enteric infection in the young pig. Vet. Rec, 95, 99
Porter, P., Kenworthy, R., Holme, D. W. and Horsefield, S. (1973). E. coli antigens as dietary additives for oral immunization of pigs. Trials with pig creep feeds. Vet. Rec, 92, 630
Porter, P., Kenworthy, R., Noakes, D. E. and Allen, W. D. (1974). Intestinal antibody secretion in the young pig in response to oral immunization with E. coli. Immunology, 27, 841
Porter, P. Kenworthy, R. and Thompson, I. (1975). Oral immunization and its significance in the prophylactic control of enteritis in the preruminant calf. Vet. Rec, 97, 24
Porter, P. and Noakes, D.E. (1970). Immunoglobulin A in bovine serum and external secretions. Biochim. Biophys. Acta, 214, 107
Porter, P., Noakes, D. E. and Allen, W. D. (1972). Intestinal secretion of immunoglobulin in the pre-ruminant calf. Immunology, 23, 299
Roy, J. B. H., Palmer, J., Shillam, K. W. G., Ingram, P. L. and Wood, P. C. (1955). The nutritive value of colostrum for the calf. 10.Relationship between the period of time that a calf house has been occupied and the incidence of scouring and mortality in young calves. Br. J. Nutr., 9, 11
Smith, J. W. (1960). The ecology of the intestinal bacteria of the calf with particular regard to E. coli. Vet. Rec, 72, 1178
Smith, H. W. (1962). Observations on the aetiology of neonatal diarrhoea (Scours) in calves. J. Path. Bact., 84, 147
Stobo, J. D. and Tomasi, T. B. (1966). A low molecular weight immunoglobulin antigenically related to IgM. J. Clin. Invest., 46, 1329
S wann Report (1969). Joint Committee on the Use of Antibiotics in Animal Husbandry and Veterinary Medicine. H.M.S.O. London.
Vaerman, J. P. (1970). Studies on IgA immunoglobulin in man and animals; Thesis, Université Catholique de Louvain
World Health Organization Technical Report (1972). Oral Enteric Bacterial Vaccines, Serial No. 500
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 MTP Press Limited
About this chapter
Cite this chapter
Porter, P., Allen, W.D. (1978). Antibody response in pigs and calves to antigens from the intestinal lumen and the efficacy of oral immunoprophylaxis against post-weaning enteric infection. In: Hemmings, W.A. (eds) Antigen Absorption by the Gut. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6609-6_9
Download citation
DOI: https://doi.org/10.1007/978-94-011-6609-6_9
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-011-6611-9
Online ISBN: 978-94-011-6609-6
eBook Packages: Springer Book Archive