Abstract
Surgeons are transplanting kidneys in ever increasing numbers—more than 10000 renal allografts have now been reported to the Transplant Registry. With related donors 75% of grafted kidneys continued to function after 2 years, compared with 50% when the donors were unrelated. The therapeutic value is obvious, but the management is largely empirical and results have improved little in the past 5 years. The basic sciences related to tissue transplantation have advanced rapidly. New serological and tissue culture techniques and chemical analysis of antigens and antibodies have produced complicated data that is almost incomprehensible to the nonspecialist. Mathematical treatment of genetic probabilities and of immunological kinetics are similarly difficult to follow for those not especially trained.
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References
Dick, Heather M., Briggs, J. I., Wood, R. F. M. and Bell, P. R. F. (1972a). Severe rejection of an HL-A identical sibling renal transplant. Tissue Antigens, 2, 345
Dick, Heather M., Boyd, Gillian A., Briggs, J. D., Wood, R. F. M. and Bell, P. R. F. (1972b). Severe rejection of an HL-A identical sibling renal transplant. Results of MLC test. Tissue Antigens, 2, 480
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© 1973 Roy Y. Calne
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Calne, R.Y. (1973). Introduction. In: Calne, R.Y. (eds) Immunological Aspects of Transplantation Surgery. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6600-3_1
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DOI: https://doi.org/10.1007/978-94-011-6600-3_1
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-011-6602-7
Online ISBN: 978-94-011-6600-3
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