Abstract
The serum fatty acid composition has been investigated in seven patients with slowly progressive multiple sclerosis and in five control individuals. The serum level of tymnodonic (C20:5 ω-3) and clupadonic acid (C22:6 ω-3) has been shown to be normal in multiple sclerosis patients. Before diet supplementation with Maxepa there was significant decrease of linolenic (C18:3) and eicosanoic (C20:1) acids, as well as an increase of palmitic acid (C 16:0) in sera of MS patients. The variation in the serum fatty acid pattern in MS patients after 1 week diet supplementation with Maxepa has been measured for the first time. There was significant increase in serum clupadonic, tymnodonic and arachi-donic acid (C 20:4 ω-6) in MS patients who have been given Maxepa. Linolenic (C 18:3) and eicosanoic (C20:1) acids remained not supplemented and palmitic acid (C16:0) was still increased. It has been suggested that the diet supplementation in slowly progressive multiple sclerosis should consist of both ω-3 and ω-6 polyunsaturated fatty acids.
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Rosnowska, M., Cendrowski, W. (1984). The effect of dietary supplementation of enriched marine oil on serum levels of ω-3 and ω-6 polyunsaturated fatty acids in multiple sclerosis. In: Gonsette, R.E., Delmotte, P. (eds) Immunological and Clinical Aspects of Multiple Sclerosis. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6352-1_22
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DOI: https://doi.org/10.1007/978-94-011-6352-1_22
Publisher Name: Springer, Dordrecht
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