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Herpes Simplex Virus Infections of the Nervous System

  • Chapter
Infectious Diseases of the Central Nervous System

Part of the book series: Neurologic Illness ((Ni))

Abstract

Herpes simplex virus is one of the group of herpes viruses responsible for a variety of human infections.1,2 These large enveloped DNA viruses, together comprising herpes simplex virus types I and II, cytomegalovirus, varicella zoster virus, and Epstein-Barr virus, are unique in that they all have the capability for persisting in humans for many years, though the sites and manner in which they persist appear to differ. Herpes simplex virus and varicella-zoster virus share the ability to produce segmental cutaneous disease which, in the case of herpes simplex, is probably related to its demonstrated potential to reside in sensory ganglia for many years. The same may be true for varicella zoster virus; direct proof of this is now emerging. Both herpes simplex virus and Epstein-Barr virus are suspected causes of human tumors, though the evidence for the latter is much more convincing. EB virus was first isolated from tumor tissues of patients with Burkitt’s lymphoma in Africa and has since been strongly implicated by DNA reassociation studies in nasopharyngeal tumors. Though a role for herpes simplex virus infection has been suspected on the basis of serologic evidence in human cervical cancer, a direct association between the virus and cervical cancer is still lacking.

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Authors
  1. J. Richard Baringer
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Editors and Affiliations

  1. Division of Neurology, Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center, Phoenix, Arizona, USA

    Richard A. Thompson M.D.

  2. Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center, Phoenix, Arizona, USA

    John R. Green M.D., F.A.C.S. (Chairman of Neurosurgery, and Chairman) (Chairman of Neurosurgery, and Chairman)

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© 1984 Spectrum Publications, Inc.

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Baringer, J.R. (1984). Herpes Simplex Virus Infections of the Nervous System. In: Thompson, R.A., Green, J.R. (eds) Infectious Diseases of the Central Nervous System. Neurologic Illness. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6332-3_2

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  • DOI: https://doi.org/10.1007/978-94-011-6332-3_2

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-6334-7

  • Online ISBN: 978-94-011-6332-3

  • eBook Packages: Springer Book Archive

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