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Current Therapy of Brain Abscess

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Infectious Diseases of the Central Nervous System

Part of the book series: Neurologic Illness ((Ni))

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Abstract

Brain abscesses present a spectrum of challenging problems in diagnosis and management. Significant advances have provided the clinician with a wide armamentarium of diagnostic and therapeutic modalities, and recent reports have noted a downward trend in mortality.1

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References

  1. Alderson, D., Strong, A.J., Ingham, H.R., and Selkon, J.B. Fifteen-year review of the mortality of brain abscess. Neurosurgery 8:1–6, 1981.

    PubMed  CAS  Google Scholar 

  2. Beller, A.J., Sahar, A., and Praiss, I. Brain abscess: Review of 89 cases over a period of 30 years. J. Neurol. Neurosurg. Psychiatry 36:757–768, 1973.

    PubMed  CAS  Google Scholar 

  3. Bhatia, R., Tandon, P.N., and Banerji, A.K. Brain abscess: an analysis of 55 cases. Int. Surg. 58:565–568, 1973.

    PubMed  CAS  Google Scholar 

  4. Brewer, N.S., MacCarty, C.S., and Wellman, W.E. Brain abscess: a review of recent experience. Ann. Intern Med. 82:571–576, 1975.

    PubMed  CAS  Google Scholar 

  5. French, L.A., and Chou, S.N. Treatment of brain abscesses. Adv. Neurol. 6:269–275, 1974.

    PubMed  CAS  Google Scholar 

  6. Gerszten, E., Dalton, H.P., and Allison, M.J. Brain abscesses: a ten year review. South. Med. J. 66:593–594, 1973.

    PubMed  CAS  Google Scholar 

  7. Jefferson, A.A. and Keogh, A.J. Intracranial abscesses. A review of treated patients over 20 years. Q.J. Med. 183:389–400, 1977.

    Google Scholar 

  8. Klug, N., and Ellams, I.D. Difficulties in the differential diagnosis of brain abscesses. Adv. Neurosurg. 9:61–67, 1981.

    Google Scholar 

  9. McCann, V.J., Kyle, T., Goodwin, C.S., and Stokes, J.B. Intracranial abscess. Med. J. Aust. 1:75–76, 1979.

    PubMed  CAS  Google Scholar 

  10. McClelland, C.J., Craig, B.F., and Crockard, H.A. Brain abscesses in Northern Ireland: a 30 year community review. J. Neurol. Neurosurg. Psychiatry 47:1043–1047, 1978.

    Google Scholar 

  11. Morgan, H., Wood, M.W. and Murphey, F. Experience with 88 consecutive cases of brain abscess. J. Neurosurg. 38:698–704, 1973.

    PubMed  CAS  Google Scholar 

  12. Samson, D.S., and Clark, K. A current review of brain abscess. Am. J. Med. 54:201–210, 1973.

    PubMed  CAS  Google Scholar 

  13. Tiyaworabun, S., Wanis, A., Nicola, N., and Thal., H.U. 34 years therapeutic experience with brain abscesses. Adv. Neurosurg. 9:48–56, 1981.

    Google Scholar 

  14. Yang, S.Y. Brain abscess: a review of 400 cases. J. Neurosurg. 55:794–799, 1981.

    PubMed  CAS  Google Scholar 

  15. Nahser, H.C., Flossdorf, G.R., and Clar, H.E. Development of brain abscesses: computerized tomogram compared with morphological studies. Adv. Neurosurg. 9:32–35, 1981.

    Google Scholar 

  16. Shaw, M.D.M., and Russell, J.A. Cerebellar abscess: a review of 47 cases. J. Neurol. Neurosurg. Psychiatry 38:429–435, 1975.

    PubMed  CAS  Google Scholar 

  17. Nissen, A.J. Intracranial complications of otogenic disease. Am. J. Otology 2:164–167, 1980.

    PubMed  CAS  Google Scholar 

  18. Ingham, H.R., Selkon, J.B., and Roxby, CM. Bacteriological study of otogenic cerebral abscesses: chemotherapeutic role of metronidazole. Br. Med. J. 2:991–993, 1977.

    PubMed  CAS  Google Scholar 

  19. deLouvois, J. The bacteriology and chemotherapy of brain abscess. J. Antimicrob. Chemother. 4:395–413, 1978.

    PubMed  Google Scholar 

  20. Ingham, H.R., Kalhag, R.M., Iharagonnei, D., High, A.S., Sengupia, R.P., and Selkon, J.B. Abscesses of the frontal lobe of the brain secondary to covert dental sepsis. Lancet 2:497–499, 1978.

    PubMed  CAS  Google Scholar 

  21. Duffner, P.K., and Cohen, M.E. Cystic fibrosis with brain abscess. Arch. Neurol. 36:27–28, 1979.

    PubMed  CAS  Google Scholar 

  22. Brandt, M., Altenburg, H., and Böhm, P. Brain abscesses in children with congenital heart disease. Adv. Neurosurg. 9:86–89, 1981.

    Google Scholar 

  23. Raimondi, A.J., Matsumoto, S., and Miller, R.A. Brain abscess in children with congenital heart disease: I. J. Neurosurg. 23:588–595, 1965.

    PubMed  CAS  Google Scholar 

  24. Fischbein, CA., Rosenthal, A., Fischer, E.G., Nadas, A.S., and Welch, K. Risk factors for brain abscess in patients with congenital heart disease. Am. J. Cardiol. 34:97–102, 1974.

    PubMed  CAS  Google Scholar 

  25. Waggener, J.D. The pathophysiology of bacterial meningitis and cerebral abscesses: an anatomical interpretation. Adv. Neurol. 6:1–17, 1974.

    PubMed  CAS  Google Scholar 

  26. Raimondi, A.J., and Samuelson, G.H. Crainiocerebral gunshot wounds in civilian practice. J. Neurosurg. 32:647–653, 1970.

    PubMed  CAS  Google Scholar 

  27. Dzenitis, A.J., and Kaisbeck, J.E. Chronic brain abscess discovered 31 years after intracerebral injury by missile. Report of a case. J. Neurosurg. 22:169–171,1965.

    PubMed  CAS  Google Scholar 

  28. Fantis, A., and Zeren, A.S. Experience with delayed chronic brain abscesses. Adv. Neurosurg. 9:90–96, 1981.

    Google Scholar 

  29. Robinson, E.F., Moiel, R.H., and Gol, A. Brain abscess 36 years after head injury. J. Neurosurg. 28:166–168, 1968.

    PubMed  CAS  Google Scholar 

  30. Karandanis, D., and Shulman, J.A. Factors associated with mortality in brain abscess. Arch. Intern. Med. 135:1145–1150, 1975.

    PubMed  CAS  Google Scholar 

  31. Lim, D.P., Liersch, R., Pothmann, R., and Seibert, H.K. Brain abscesses in childhood. Adv. Neurosurg. 9:76–80, 1981.

    Google Scholar 

  32. Muhtaroglu, U., Klinge, H., and Lemke, J. Intrasellar abscesses. Adv. Neur-osurg. 9:97–99, 1981.

    Google Scholar 

  33. Claveria, L.E., duBoulay, G.H., and Moseley, I.F. Intracranial infections: investigation by computerized axial tomography. Neuroradiology 12:59–71, 1976.

    PubMed  CAS  Google Scholar 

  34. Crocker, E.F., McLaughlin, A.F., Morris, J.G., Benn, R., McLeod, J.G., and Allsop, J.L. Technetium brain scanning in the diagnosis and management of cerebral abscess. Am. J. Med. 56:192–201, 1974.

    PubMed  CAS  Google Scholar 

  35. Nielsen, H., and Gyldensted, C. Computed tomography in the diagnosis of cerebral abscess. Neuroradiology 22:207–217, 1977.

    Google Scholar 

  36. Nielsen, H., and Halaburt, H. Cerebral abscesses with special reference to the angiographic changes. Neuroradiology 12:73–78, 1976.

    PubMed  CAS  Google Scholar 

  37. Wood, J.H., Doppman, J.L., Lightfoote, W.E., Girton, M., and Ommaya, A.K. Role of vascular proliferation on angiographic appearance and encapsulation of experimental traumatic and metastatic brain abscesses. J. Neur-osurg. 48:264–273, 1978.

    CAS  Google Scholar 

  38. Shaw, M.D.M., and Russell, J.A. Value of computed tomography in the diagnosis of intracranial abscess. J. Neurol. Neurosurg. Psychiatry 40:214–220, 1977.

    PubMed  CAS  Google Scholar 

  39. Whelan, M.A., and Hilal, S.K. Computed tomography as a guide in the diagnosis and follow-up of brain abscesses. Radiology 135:663–671, 1980.

    PubMed  CAS  Google Scholar 

  40. Danzinger, A., Price, H., and Schechter, M.M. An analysis of 113 intracranial infections. Neuroradiology 29:31–34, 1980.

    Google Scholar 

  41. Mauersberger, W. The determination of absorption values as an aid in computer tomographic differentiation between cerebral abscess and gliob-lastoma. Adv. Neurosurg. 9:36–40, 1981.

    Google Scholar 

  42. Weisberg, L.A. Cerebral computerized tomography in intracranial inflammatory disorders. Arch. Neurol. 37:137–142, 1980.

    PubMed  CAS  Google Scholar 

  43. Feely, M.P., and Dempsey, P.J. Assessment of the postoperative course of excised brain abscesses by computerized tomography. Neurosurgery 5:49–52, 1979.

    PubMed  CAS  Google Scholar 

  44. Ohaegbulam, S.C., and Saddeqi, N.U. Experience with brain abscesses treated by simple aspiration. Surg. Neurol. 13:289–291, 1980.

    PubMed  CAS  Google Scholar 

  45. Stephanov, S. Experience with multiloculated brain abscesses. J. Neurosurg. 49:199–203, 1978.

    PubMed  CAS  Google Scholar 

  46. Van Alphen, H.A.M., and Dreissen, J.J.R. Brain abscess and subdural em-pyema: factors influencing mortality and results of various surgical techniques. J. Neurol. Neurosurg. Psychiatry 39:481–490, 1976.

    PubMed  Google Scholar 

  47. Black, P., Graybill, J.R., and Charache, P. Penetration of brain abscess by systemically administered antibiotics. J. Neurosurg. 38:705–709, 1973.

    PubMed  CAS  Google Scholar 

  48. Wise, B.L., and Gleason, C.A. CT-directed stereotactic surgery in the management of brain abscess. Ann. Neurol. 6:457, 1979.

    PubMed  CAS  Google Scholar 

  49. Choudhury, A.R., Taylor, J.C., and Whitaker, R. Primary excision of brain abscess. Br. Med. J. 2:1119–1121, 1977.

    PubMed  CAS  Google Scholar 

  50. Garfield, J. Brain abscesses and focal suppurative infections, Infections of the Nervous System, Part 1. Handbook of Clinical Neurology, Vol. 33. In: Vinken, P.J., Bruyn, G. W., eds. Amsterdam/New York/Oxford: North Holland, pp. 107–147, 1978.

    Google Scholar 

  51. Rosenblum, M.L., Hoff, J.T., Norman, D., Edwards, M.S., and Berg, B.O. Nonoperative treatment of brain abscesses in selected high-risk patients. J. Neurosurg. 52:217–225, 1980.

    PubMed  CAS  Google Scholar 

  52. Heineman, H.S., Braude, A.I., and Osterholdm, J.L. Intracranial suppurative disease: early presumptive diagnosis and successful treatment without surgery. J.A.M.A. 218:1542–1547, 1971.

    PubMed  CAS  Google Scholar 

  53. Berg, B., Franklin, G., Cuneo, R., Boldrey, E., and Strimling, B. Nonsurgical cure of brain abscess: early diagnosis and follow-up with computed tomography. Ann. Neurol. 3:474–478, 1978.

    PubMed  CAS  Google Scholar 

  54. Kamin, M., and Biddle, D. Conservative management of focal intracerebral infection. Neurology 31:103–106, 1981.

    PubMed  CAS  Google Scholar 

  55. Kobrine, A.I., Davis, D.O., and Rizzoli, H.V. Multiple abscesses of the brain: a case report. J. Neurosurg. 54:93–97, 1981.

    PubMed  CAS  Google Scholar 

  56. Kottas, M., and Smith, L.G. A possible new approach to the management of brain abscesses. Infection 6:81–83, 1978.

    PubMed  CAS  Google Scholar 

  57. Liston, T.E., Tomasovic, J.J., and Stevens, E.A. Early diagnosis and management of cerebritis in a child. Pediatrics 65:484–486, 1979.

    Google Scholar 

  58. Rotheram, E.B., and Kessler, L.A. Use of computerized tomography in nonsurgical management of brain abscesses. Arch. Neurol. 36:25–26, 1979.

    PubMed  Google Scholar 

  59. Stevens, E.A., Norman, D., Kramer, R.A., Messina, A.B., and Newton, T.H. Computed tomographic brain scanning in intraparenchymal pyogenic abscesses. A.J.R. 130:111–114, 1978.

    CAS  Google Scholar 

  60. Traub, W.H. Brain abscess and acute purulent meningitis: recent developments in clinical microbiology. Adv. Neurosurg. 9:3–24, 1981.

    Google Scholar 

  61. Ingham, H.R., Selkon, J.B., and Roxby, C.M. The bacteriology and chemotherapy of otogenic cerebral abscesses. J. Antimicrob Chemother. 4 (Suppl. C):63–69, 1978.

    PubMed  Google Scholar 

  62. Everett, E.D., and Strausbaugh, L.J. Antimicrobial agents and the central nervous system. Neurosurgery 6:691–714, 1980.

    PubMed  CAS  Google Scholar 

  63. Kaplan, S.L., Mason, E.O., Garcia, H., Kvernland, S.J., Loiselle, E.M., Anderson, D.C., Mintz, A.A., and Feigin, R.D. Pharmacokinetics and cerebro-spinal fluid penetration of moxalactam in children with bacterial meningitis. J. Pediatr. 98:152–157, 1981.

    PubMed  CAS  Google Scholar 

  64. Schaad, U.B., McCracken, G.H., Threlkeld, N., and Thomas, M.L. Clinical evaluation of a new broad-spectrum oxa-betalactam antibiotic, moxalactam, in neonates and infants. J. Pediatr. 98:129–136, 1981.

    PubMed  CAS  Google Scholar 

  65. Dillon, H.C. Studies of moxalactam for gram-negative and Haemophilus influenzae meningitis: an appraisal. J. Pediatr. 99:907–908, 1981.

    PubMed  Google Scholar 

  66. Thirumoorthi, M.C., Buckley, J.A., Aravind, M.K., Kauffman, R.E., and Dajani, A.S. Diffusion of moxalactam into the cerebrospinal fluid in children with bacterial meningitis. J. Pediatr. 99:975–979, 1981.

    PubMed  CAS  Google Scholar 

  67. Quartey, G.R.C., Johnston, J.A., and Rozdilsky, B. Decadron in the treatment of cerebral abscess. J. Neurosurg. 45:301–310, 1976.

    PubMed  CAS  Google Scholar 

  68. Bohl, L, Wallenfang, T., Bothe, H., and Schurmann, K. The effect of glucocorticoids in the combined treatment of experimental brain abscesses in cats. Adv. Neurosurg. 9:125–128, 1981.

    CAS  Google Scholar 

  69. Wallenfang, T., Reulen, H.J., and Schurmann, K. Therapy of brain abscess. Adv. Neurosurg. 9:41–47, 1981.

    Google Scholar 

  70. Entzian, W. The brain abscess. A search for risk factors. Adv. Neurosurg. 9:68–75, 1981.

    Google Scholar 

  71. Danzinger, J., Allen, K.L., and Bloch, S. Brain-stem abscess in childhood. J. Neurosurg. 40:391–393, 1974.

    Google Scholar 

  72. Van Gilder, J.C., Allen, W.E., and Lesser, R.A. Pontine abscess: survival following surgical drainage. Case report. J. Neurosurg. 40:386–390, 1974.

    Google Scholar 

  73. Carey, M.E., Chou, S.N., and French, L.A. Experience with brain abscesses. J. Neurosurg. 36:1–9, 1972.

    PubMed  CAS  Google Scholar 

  74. Legg, N.J., Gupta, P.C., and Scott, D.F. Epilepsy following cerebral abscess: a clinical and EEG study of 70 patients. Brain 96:259–268, 1973.

    PubMed  CAS  Google Scholar 

Bibliography

  • Balakrishnan, D., and Natarajan, M. Intracranial abscesses. Indian. Med. Assoc. 57:87–90, 1971.

    Google Scholar 

  • Britt, R.H., Enzmann, D.R., and Yeager, A.S. Neuropathological and computerized tomographic findings in experimental brain abscess J. Neurosurg. 55:590–603, 1981.

    PubMed  CAS  Google Scholar 

  • Brook, I. Bacteriology of intracranial abscess in children. J. Neurosurg. 54:484–488, 1981.

    PubMed  CAS  Google Scholar 

  • Bruckner, O., Collmann, H., Alexander M., and Wagner, J. Concentrations of antibiotics in cerebral abscess fluid and cerebrospinal fluid. Adv. Neurosurg. 9:113–119, 1981.

    Google Scholar 

  • Byrne, E., Brophy, B.P., and Perrett, L.V. Nocardia cerebral abscesses: new concepts in diagnosis, management and prognosis. J. Neurol. Neurosurg. Psychiatry 42:1038–1045, 1979.

    PubMed  CAS  Google Scholar 

  • Carey, M.E., Chou, S.N., and French, L.A. Long-term neurological residua in patients surviving brain abscess with surgery. J. Neurosurg. 54:652–656, 1971.

    Google Scholar 

  • Enzmann, D.R., Britt, R.H., and Yeager, A.S. Experimental brain abscess evolution: computed tomographic and neuropathologic correlation. Radiology 133:113–122, 1979.

    PubMed  CAS  Google Scholar 

  • Ettinger, M.G. Brain abscess. In: Clinical Neurology, Vol. 2. Baker, A.B. and Baker, L.H., eds. Philadelphia: Harper and Row, pp. 1–35, 1981.

    Google Scholar 

  • Gleason, C.A., Wise, B.L., and Feinstein, B. Stereotactic localization (with computerized tomographic scanning), biopsy, and radiofrequency treatment of deep brain lesions. Neurology 2:217–222, 1978.

    CAS  Google Scholar 

  • Heath, L.K., Goldstein, E., and Dublin, A. Considerations in diagnosing brain abscesses with computerized axial tomography. Arch. Intern. Med. 138:628–629, 1978.

    PubMed  CAS  Google Scholar 

  • Jokipii, A.M.M., Myllyla, V.V., Hokkanen, E., and Jokipii, L. Penetration of the blood brain barrier by metronidazole and tinidazole. J. Antimicrob. Chemother. 3:239–245, 1977.

    PubMed  CAS  Google Scholar 

  • Joubert, M.J., and Stephanov, S. Computerized tomography and surgical treatment in intracranial suppuration: report of 30 consecutive unselected cases of brain abscess and subdural empyema. J. Neurosurg. 47:73–78, 1977.

    PubMed  CAS  Google Scholar 

  • Kaufman, D.M., and Leeds, N.E. Computed tomography (CT) in the diagnosis of intracranial abscesses: brain abscess, subdural empyema, and epidural empyema. Neurology 27:1069–1073, 1977.

    PubMed  CAS  Google Scholar 

  • Klinger, M., Wallenfang, T., and Bergsten, B. Newer antibiotics for brain abscess treatment investigated in animal experiments. Adv. Neurosurg. 9:106–112, 1981.

    CAS  Google Scholar 

  • Kunze, S. Symptomatology and diagnosis of brain abscesses. Adv. Neurosurg. 9:25–31, 1981.

    Google Scholar 

  • Lott, T., ElGammal, T., Dasilva, R., Hanks, D., and Reynolds, J. Evaluation of brain and epidural abscesses by computed tomography. Radiology 122:371–376, 1977.

    PubMed  CAS  Google Scholar 

  • deLouvois, J., Gortvai, P., and Hurley, R. Bacteriology of abscesses of the central nervous system: a multicentre prospective study. Br. Med. J. 2:981–984, 1977.

    PubMed  Google Scholar 

  • deLouvois, J., Gortavi, P., and Hurley, R. Antibiotic treatment of abscesses of the central nervous system. Br. Med. J. 2:985–987, 1977.

    PubMed  Google Scholar 

  • Molinari, G.G., Smith, L., Goldstein, M.N., and Satran, R. Brain abscess from septic cerebral embolism: an experimental model. Neurology 23:1205–1210, 1973.

    PubMed  CAS  Google Scholar 

  • Moussa, A.H., and Dawson, B.H. Computed tomography and the mortality rate in brain abscess. Surg. Neurol. 10:301–304, 1978.

    PubMed  CAS  Google Scholar 

  • New, P.F.J., Davis, K.R., and Ballantine, H.T. Computed tomography in cerebral abscess. Radiology 121:641–646, 1976.

    PubMed  CAS  Google Scholar 

  • Pendi, G., Schuster, H., Perneczky, A., and Koos, W. Surgical treatment of brain abscesses with special consideration of acute and subacute abscesses. Adv. Neurosurg. 9:57–60, 1981.

    Google Scholar 

  • Price, H., and Danzinger, A. The role of computerized tomography in the diagnosis and management of intracranial abscesses. Clin. Radiol. 29:571–577,1978.

    PubMed  CAS  Google Scholar 

  • Remmler, D., and Boles, R. Intracranial complications of frontal sinusitis. Laryngoscope 90:1814–1824, 1980.

    PubMed  CAS  Google Scholar 

  • Resch, J.A., and Sung, J.H. Brain abscess and diffuse suppurative encephalitis. In: Clinical Neurology. Vol. 2. Baker, A.B., Baker, L.H., eds. Philadelphia: Harper and Row, pp. 1–26, 1980.

    Google Scholar 

  • Rosenblum, M.L., Hoff, J.T., Norman, D., Weinstein, P.R., and Pitts, L. Decreased mortality from brain abscesses since advent of computerized tomography. J. Neurosurg. 49:658–668, 1978.

    PubMed  CAS  Google Scholar 

  • Schuster, H., and Koos, W. Brain abscess in children. Adv. Neurosurg. 9:81–85, 1981.

    Google Scholar 

  • Warner, J.F., Perkins, R.L., and Cordero, L. Metronidazole therapy of anaerobic bacteremia, meningitis, and brain abscess. Arch. Intern. Med. 139:167–169, 1979.

    PubMed  CAS  Google Scholar 

  • Wood, J.H., Lightfoote, W.E., and Ommaya, A.K. Cerebral abscesses produced by bacteria implantation and septic embolisation in primates. J. Neurol. Neurosurg. Psychiatry 42:63–69, 1979.

    PubMed  CAS  Google Scholar 

  • Zimmerman, R.A., Bilaniuk, L.T., Shipkin, P.M., Gilden, D.H., and Murtagh, F. Evolution of cerebral abscess: correlation of clinical features with computed tomography, a case report. Neurology 27:14–19, 1977.

    PubMed  CAS  Google Scholar 

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Authors
  1. Daniel G. Nehls
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  2. Robert M. Crowell
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Editors and Affiliations

  1. Division of Neurology, Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center, Phoenix, Arizona, USA

    Richard A. Thompson M.D.

  2. Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center, Phoenix, Arizona, USA

    John R. Green M.D., F.A.C.S. (Chairman of Neurosurgery, and Chairman) (Chairman of Neurosurgery, and Chairman)

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Nehls, D.G., Crowell, R.M. (1984). Current Therapy of Brain Abscess. In: Thompson, R.A., Green, J.R. (eds) Infectious Diseases of the Central Nervous System. Neurologic Illness. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6332-3_13

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  • DOI: https://doi.org/10.1007/978-94-011-6332-3_13

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