Skip to main content

Incidence and Prevention of Infection after Neurosurgical Operations

  • Chapter
Infectious Diseases of the Central Nervous System

Part of the book series: Neurologic Illness ((Ni))

Abstract

At about the time of the Boston Tea Party, King George III of England was troubled by a sebaceous cyst of the scalp. He summoned the renowned surgeon Sir Astley Cooper to attend to him and remove the wen. Sir Astley did so successfully, but with reluctance. “Wounds of the scalp,” he is quoted to have said, “are not so trifling as they first might appear. Inflammation very often follows, erisipelas etc, and many die in consequence of the injury done to the scalp ... I was called upon to remove a tumor from the scalp of a lady; it was unfortunately attached to the tendon of the occipito-frontalis muscle and I necessarily had to remove a part of this tendon. The operation was done on a Wednesday, she seemed quite well after its removal, but on Sunday she was seized with rigor, succeeded by heat—she became feverish and on the Tuesday she died. Therefore, you will, I trust, be upon your guard and never make an unnecessary cut on any part of the scalp for such a practice is dangerous and you will not know what may follow such a wound.”1

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Cope, Z. Sidelights on the History of Medicine, pp. 157–158. London: Butterworth, 1957.

    Google Scholar 

  2. Lister, J. On the antiseptic principle in the practice of surgery. Lancet 2:353–356, 1867.

    Article  Google Scholar 

  3. Saugous, E. (ed.). Annual of the Universal Medical Sciences, p. 15. Philadelphia: Davis, 1885. (Quoted from Weekly Medical News, 1877.).

    Google Scholar 

  4. MacCallum, W. G. William Stewart Hoisted, p. 81. Baltimore: Johns Hopkins, 1920.

    Google Scholar 

  5. Wright, R. L. Postoperative Craniotomy Infections. Springfield, IL: Charles C Thomas, 1966.

    Google Scholar 

  6. Cushing, H. Concerning the results of operation for brain tumor. JAMA 64:189–195, 1915.

    Article  Google Scholar 

  7. Cushing, H. Surgery of the head. In: Surgery, Its Principles and Practice, vol. 3, W. W. Keen (ed.), pp. 17–276. Philadelphia: W. B. Saunders, 1912.

    Google Scholar 

  8. Cushing, H. Tumors of the Neruus acusticus and the Syndrome of the Cerebellopontine Angle. Philadelphia: W. B. Saunders, 1917.

    Google Scholar 

  9. Cushing, H. Experiences with the cerebellar astrocytomas: A critical review of seventy-six cases. Surg. Gynecol. Obstet. 52:129–204, 1931.

    Google Scholar 

  10. Cushing, H., and Eisenhardt, L. Meningiomas, Their Classification, Regional Behaviour, Life History and Surgical End Results. Springfield, IL: Charles C Thomas, 1938.

    Google Scholar 

  11. Cairns, H. Bacterial infection during intracranial operations. Lancet 2:1193–1198, 1939.

    Article  Google Scholar 

  12. Wright, R. L. A survey of possible etiologic agents in postoperative craniotomy infections. J. Neurosurg. 25:125–132, 1966.

    Article  PubMed  CAS  Google Scholar 

  13. Wright, R. L. Septic Complications of Neurosurgical Spinal Procedures. Springfield, IL: Charles C Thomas, 1970.

    Google Scholar 

  14. Balch, R. E. Wound infections complicating neurosurgical procedures. J. Neurosurg. 26:41–45, 1967.

    Article  PubMed  CAS  Google Scholar 

  15. Ritter, M.A., Eitzer, H. E., French, M. L. V., and Hart, J. B. The effect that time, touch, and environment have upon bacterial contamination of instruments during surgery. Ann. Surg. 284:642–644, 1976.

    Article  Google Scholar 

  16. Berger, S. A., Nagar, H., and Weitzman, S. Prophylactic antibot antibiotics in surgical procedures. Surg. Gynecol. Obstet. 146:469–475, 1978.

    PubMed  CAS  Google Scholar 

  17. Chodak, G. W., and Plaud, M. E. Use of systemic antibiotics for prophylaxis in surgery. Arch. Surg. 112:326–334, 1977.

    Article  PubMed  CAS  Google Scholar 

  18. Jacoby, J., Mandell, L. A., and Weinstein, L. The chemoprophylaxis of infection. Med. Clin. North Am. 62:1083–1098, 1978.

    PubMed  CAS  Google Scholar 

  19. Lewis, R. T. Antibiotic prophylaxis in surgery. Can. J. Surg. 24:561–566, 1981.

    PubMed  CAS  Google Scholar 

  20. Antimicrobiologic prophylaxis for surgery. Med. Lett. 23:77–80, 1981.

    Google Scholar 

  21. Moellering, R. C, Kuntz, L. J., Poitras, J. W., et al. Microbiologic basis for the rational use of prophylactic antibiotics. South. Med. J. 70 (suppl. 1):8–14, 1977.

    Article  PubMed  Google Scholar 

  22. Ericson, C, Lidgren, L., and Lindberg, L. Cloxacillin in the prophylaxis of postoperative infection of the hip. J. Bone Joint Surg. (Am.) 55:808–813, 1973.

    CAS  Google Scholar 

  23. Haines, S. J., and Goodman, M. L. Antibiotic prophylaxis of postoperative neurological wound infection. J. Neurosurg. 56:103–105, 1982.

    Article  PubMed  CAS  Google Scholar 

  24. Haines, S. J. Systemic antibiotic prophylaxis in neurological surgery. Neurosurgery 6:355–361, 1980.

    Article  PubMed  CAS  Google Scholar 

  25. Malis, L. I. Prevention of neurological infection by intraoperative antibiotics. Neurosurgery 5:339–343, 1979.

    Article  PubMed  CAS  Google Scholar 

  26. Horwitz, N.G., and Curtin, J. A. Prophylactic antibiotics and wound infections following laminectomy for lumbar disc herniation. J. Neurosurg. 43:727–737, 1975.

    Article  PubMed  CAS  Google Scholar 

  27. Quartey, G. R. C., and Polyzoidis, K. Intraoperative antibiotic prophylaxis in neurosurgery: A clinical study. Neurosurgery 8:669–671, 1981.

    Article  PubMed  CAS  Google Scholar 

  28. Savitz, M. H., and Katz, S. K. Rationale for prophylactic antibiotics in neurosurgery. Neurosurgery 9:142–144, 1981.

    Article  PubMed  CAS  Google Scholar 

  29. Landesman, S. H., Corrado, M. L., Shah, P. M., et al. Past and current roles for cephalosporin antibiotics in the treatment of meningitis. Am. J. Med. 71:693–703, 1981.

    Article  PubMed  CAS  Google Scholar 

  30. Burke, J. F. The effective period of preventive antibiotic action in experimental incisions and dermal lesions. Surgery 50:161–168, 1961.

    PubMed  CAS  Google Scholar 

  31. Rodeheaver, G., Edgerton, M. T., Smith, S., King, H., Kurtz, I., and Edlick, R. F. Antimicrobial prophylaxis of contaminated tissues containing suture implants. Am. J. Surg. 133:609–611, 1977.

    Article  PubMed  CAS  Google Scholar 

  32. Halasz, N. A. Wound infection and topical antibiotics. Arch. Surg. 112:1240–1244, 1977.

    Article  PubMed  CAS  Google Scholar 

  33. Krizek, T. J., and Robson, M. C. Biology of surgical infection. Surg. Clin. North Am. 55:1261–1267, 1975.

    PubMed  CAS  Google Scholar 

  34. Caldwell, J. R., and Cluff, L. E. Adverse reactions to antimicrobial agents. JAMA 230:77–80, 1974.

    Article  PubMed  CAS  Google Scholar 

  35. Schonholtz, G. J. Maintenance of aseptic barriers in the conventional operating room. J. Bone Joint Surg. 58A:439–445, 1976.

    Google Scholar 

  36. Wright, R. L., and Burke, J. F. Effect of ultraviolet radiation on postoperative neurosurgical sepsis. J. Neurosurg. 31:533–537, 1969.

    Article  PubMed  CAS  Google Scholar 

  37. Woodhall, B., Neill, R. G., and Dratz, H. M. Ultraviolet radiation as an adjunct in the control of post-operative neurosurgical infection. II. Clinical experience, 1938-1948. Ann. Surg. 129:820–825, 1949.

    Article  Google Scholar 

  38. Kourtopoulos, H., and Burman, L. G. Prophylaxis of neurosurgical infections by improverd preoperative disinfection of the scalp. Scand. J. Infect. Dis. 11:175–176, 1979.

    PubMed  CAS  Google Scholar 

  39. Quadery, L. A., Medlery, A. V., and Miles, J. Factors affecting the incidence of wound infection in neurosurgery. Acta Neurochir. (Wein) 39:133–141, 1977.

    Article  CAS  Google Scholar 

  40. Wyler, A. R., and Kelly, W. A. Use of antibiotics with external ventriculos-tomies. J. Neurosurg. 37:185–187, 1972.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Spectrum Publications, Inc.

About this chapter

Cite this chapter

Dagi, T.F., Ojemann, R.G., Zervas, N.T. (1984). Incidence and Prevention of Infection after Neurosurgical Operations. In: Thompson, R.A., Green, J.R. (eds) Infectious Diseases of the Central Nervous System. Neurologic Illness. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6332-3_10

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-6332-3_10

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-6334-7

  • Online ISBN: 978-94-011-6332-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics