Abstract
Despite impressive achievements in the rehabilitation of spinal cord injured subjects, the following important areas of research have not been adequately investigated: (1) the general underlying pathophysiologic problems that occur in traumatically paralyzed subjects who undergo osteoporosis, periarticular bone formation, episodic hypertensive crises, and so forth; (2) mitigation of serious dysfunction by vigorous pharmacologic or surgical intervention to preserve as much sensory and motor function as possible, or both; and (3) the possibility of the elimination of paralysis per se.
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References
Cajal, S., and Ramon, Y. Degeneration and Regeneration of the Nervous System, Hafner, New York (1928).
Coyle, J.T., and Axelrod, J., J. Neurochem. 19: 449–459 (1972).
de la Torre, J.C., Johnson, C.M., Harris, L.H., Kajihara, K. and Mullan, S., Surg. Neurol. 2:5–11 (1974).
Flamm, E.W., Viau, A.T., Ransohoff, J., and Naftchi, N.E., Neurology 26: 664–666.
Griffiths, I.R., J. Neurol. Sci. 27: 529–544 (1976).
Hedeman, L.S., Shellenberger, M.K., and Gordon, J.H., J. Neurosurg. 40: 37–51 (1974).
Jarrot, B., J. Neuroehem. 18: 7–16 (1971).
Lamprecht, F., and Coyle, J.T., Brain Res. 41: 503–506 (1972).
Levitt, M., Spector, S., Sjoerdsma, A., and Udenfriend, S., J. Pharm. Exper. Therap. 148: 1–8 (1965).
Molinoff, P.B., Weinshilboum, R., and Axelrod, J., J. Pharmacol. Exp. Therap. 178: 425–431 (1971).
Naftchi, N.E., Lowman, E.W., Sell, G.H., and Rusk, H.A., Arch. Phys. Med. Rehabil. 53: 357–362 (1972).
Naftchi, N.E., Wooten, G.F., Lowman, E.W., and Axelrod, J., Circ. Res. 35: 850–861 (1974).
Naftchi, N.E., Demeny, M., Lowman, E.W., and Tuckman, J., Circ. 57 (No. 2): 336–341 (1978).
Naftchi, N.E., Demeny, M., DeCrescito, V., Tomasula, J.J., Flamm, E.S., and Campbell, J.B., J. Neurosurg. 40: 52–57 (1974).
Naftchi, N.E., and Tuckman, J., Am. Heart J. 97 (No. 4): 536–538 (1979).
Naftchi, N.E., Demeny, M., Flamm, E.S., and Lowman, E.W., Catecholamines and Stress, Pergamon Press, Great Britain, p. 367–375 (1976).
Osterholm, J.L. and Mathews, G.J., J. Neurosurg. 36: 386–394 (1972).
Osterholm, J.L., and Mathews, G.J., J. Neurosurg. 36: 395–401 (1972).
Raisman, G., Philos. Trans. R. Soc (Biol) 278: 349–359 (1977).
Raisman, G., and Field, P.M., Brain Res. 50: 241–264 (1973).
Rothman, J.E., and Engelman, D.M., Nature 237: 24–44 (1972).
Schoultz, T.W., and DeLuca, D.C., Life Sci. 15: 1485–1495 (1974).
Strittmatter, W.J., Hirata, F., and Axelrod, J., Science 204: 1205–1207 (1979).
Vise, W.M., Yashon, W., and Hunt, W.E., J. Neurosurg. 40: 76–82 (1974).
Weissman, G., New Engl. J. Med. 273: 1084–1090 (1965).
Wurtman, R.J., Chou, C., and Rose, C. J., Pharmacol. Exp. Therap. 174: 351–356 (1970).
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Naftchi, N.E., Demeny, M., Demopoulos, H., Flamm, E. (1982). Effect of Pharmacological Agents on Normalization of Molecular and Histologic Dysfunction Following Traumatic Injury to the Spinal Cord. In: Naftchi, N.E. (eds) Spinal Cord Injury. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6305-7_3
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DOI: https://doi.org/10.1007/978-94-011-6305-7_3
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-011-6307-1
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