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The Neural Basis of Behavior pp 207–227Cite as

Peptides in Affective Disorders

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Abstract

The affective disorders are mania and depression. Depression, more than mania, has been subject to a variety of systems of subclassification (Schatzberg, 1976). Since both mania and depression tend notoriously to recur, it is often possible in a given patient to base diagnosis on life history (Mazure and Gershon, 1979). Thus, one may speak of a depressed patient as showing either the bipolar or the unipolar form of the disorder; respectively, the patient has or has not suffered a previous manic attack. “Mania” almost always implies bipolar affective disorder, for mania without diagnosable episodes of depression, i.e., unipolar mania, is rare. This simple classification, now generally accepted, corresponds reasonably well to an assortment of biological findings (Goodwin and Potter, 1976) and treatment responses (Schildkraut et al., 1976). Whenever possible, we shall use it in the discussion that follows.

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Authors
  1. A. J. Prange Jr.
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  2. P. T. Loosen
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Editors and Affiliations

  1. Alfred I. duPont Institute, Wilmington, Delaware, USA

    Alexander L. Beckman Ph.D. (Senior Research Scientist) (Senior Research Scientist)

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© 1982 Spectrum Publications, Inc.

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Prange, A.J., Loosen, P.T. (1982). Peptides in Affective Disorders. In: Beckman, A.L. (eds) The Neural Basis of Behavior. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6302-6_11

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  • DOI: https://doi.org/10.1007/978-94-011-6302-6_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-6304-0

  • Online ISBN: 978-94-011-6302-6

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