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Organ Preservation pp 77–81Cite as

The dynamics of regional blood flow after ischaemic trauma of the rat kidney

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Abstract

The vascular resistance increases in kidneys subjected to ischaemic trauma, be it warm ischaemia1, cold ischaemia2, or cold continuous perfusion3. By reperfusion after different periods of hypothermic storage using a cold colloidal perfusate it was shown that this increased resistance was more pronounced in the deeper parts of the renal cortex and subsequently in the renal medulla2. This same pattern of regional perfusion was found in recipients immediately after transplantation4. The functional characteristics as studied by micropuncture techniques in transplanted kidneys also support the conclusion that the renal medulla is of primary interest for the understanding of the pathophysiology of acute renal failure after ischaemic trauma5. The observation of medullary vascular congestion in humans6 and other species7,8 supports this statement.

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References

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Authors
  1. L. Frödin
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  2. L. Karlberg
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  3. Ö. Källskog
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  4. B. J. Norlén
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  5. M. Wolgast
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Editor information

Editors and Affiliations

  1. MRC Medical Cryobiology Group, University Department of Surgery, Douglas House,Trumpington Road, CB2 2AH, Cambridge, UK

    D. E. Pegg

  2. Department of Nephrology, University Hospital, DK-5000, Odense C, Denmark

    I. A. Jacobsen

  3. Department of Surgery, University of California Medical Center, 225 Dickinson Street, 92103, San Diego, California, USA

    N. A. Halasz

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© 1982 MTP Press Limited

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Frödin, L., Karlberg, L., Källskog, Ö., Norlén, B.J., Wolgast, M. (1982). The dynamics of regional blood flow after ischaemic trauma of the rat kidney. In: Pegg, D.E., Jacobsen, I.A., Halasz, N.A. (eds) Organ Preservation. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6267-8_8

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  • DOI: https://doi.org/10.1007/978-94-011-6267-8_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-6269-2

  • Online ISBN: 978-94-011-6267-8

  • eBook Packages: Springer Book Archive

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