Abstract
Many workers have suggested an association between schizophrenia and alcoholism. If this is so, the recognition of chronic excess alcohol intake in both disorders is of obvious diagnostic importance. Annual expenditure on alcoholic beverages in the United Kingdom is in excess of £2000 million, and the equivalent of more than 71 of absolute alcohol is consumed annually per head of population. It has been estimated that more than 2% of the adult population or more than 750, 000 people drink excessively and that more than 1096 of admissions to male medical wards have a drinking problem (Hetzel, 1975; Hore, 1977).
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References
Baglin, M. C., Bernot, J. L., Bremond, J. L., Lamy, J., Leraux, M. E. and Weill, J. (1976). Efficacité comparés du volume globulaire moyen (VGM) et de la gamma-glutamyltransferase (βGT) serique comme tests de triage des buveurs excessifs d’alcool. Clin. Chin. Acta. 68, 321
Bailey, M. B., Haberman, P. W. and Steinberg, J. (1969). Millbank Memorial Fund Quarterly, 47, 235. Quoted bv Hamlyn A. N. (1975). Blood ethanol in liver disease. Lancet, ii, 991
Hamlyn, A. N., Brown, A. J., Sherlock, S. and Baron, D. N. (1975). Casual blood-ethanol estimations in patients with chronic liver disease. Lancet, ii, 345
Herbert, V., Zalusky, R. and Davidson, C. S. (1964). Correlation of folate deficiency with alcoholism and associated macrocytosis; anemia and liver disease. Ann. Intern. Med., 58, 977
Hetzel, B. S. (1975). Tobacco and alcohol. Medicine. II, 5, 224
Hore, B. D. (1977). Clinical features of alcoholism. Br. J. Hasp. Med.. August, 106
Lamy, J., Aron, E., Bernot, J. L. and Weill, J. (1976). GGTP activity as a test for the diagnosis, of excessive alcohol intake. In (G. Siest, and D. S. Young). (eds.) Drug Interference and Drug Measurement in Clinical Chemistry, pp. 42–47. (Basel: Karger)
Moore, M. R. and Goldberg, A. (1975). Some biochemical responses to ethanol in man. INSERM/MRC Symposium Franco-Brittanique sur l’Alcoolisme. 54, 101
Morgan, M. Y., Milsom. J. P. and Sherlock, S. (1977). Ratio of plasma α-amino-n-butyric acid to leucine as an empirical marker of alcoholism. Science. 197, 1183
Robinson, A. G. and Loeb, J. N. (1971). Ethanol ingestion — commonest cause of elevated plasma osmolality. N. Engl. J. Med., 284, 1253
Rosalki, S. B. (1974). Détermination de la gamma-glutamyltranspeptidase chez les alcooliques et chez les buveurs d’habitude. Proceedings Symposium. Dépistage precoce de l’intoxication alcoolique à l’aide d’um test biologique: le dosage de la gamma-glutamyl-transpeptidase. (Paris:Boehringer Mannheim)
Rosalki, S. B. (1977). Enzyme tests for alcoholism. Rev. Epidemiol. Med. Soc. Sante Publique, 25, 147
Rosalki, S. B. and Rau, D. (1972). Serum γ-glutamyl transpeptidase activity in alcoholism Clin. Chim. Acta, 39, 41
Rosalki, S. B., Rau, D., Lehmann, D. and Prentice, M. (1970). Determination of serum γ-glutamyl transpeptidase activity and its clinical applications. Ann. Clin. Biochem., 7, 143
Rutherford, W. H. (197 7). Diagnosis of alcohol ingestion in mild head injuries. Lancet, i, 1021
Shaw, S., Stimmel, B. and Lieber, C. S. (1976). Plasma alpha-amino-n-butyric acid to leucine ratio: An emperical biochemical marker of alcoholism. Science, 194, 1057
Silberfarb, P. M. (1976). Recognising alcoholism early by physical signs. Postgrad. Med., 59, 79
Wu, A., Chanarin, I. and Levi, A. J. (1974). Macrocytosis of chronic alcoholism. Lancet, i, 829
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Rosalki, S.B. (1978). Screening tests for alcoholism. In: Hemmings, G., Hemmings, W.A. (eds) The Biological Basis of Schizophrenia. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6206-7_25
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DOI: https://doi.org/10.1007/978-94-011-6206-7_25
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-011-6208-1
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