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Polarity of Epithelial Cells in Relation to Transepithelial Transport in Kidney and Intestine

  • Chapter
Intestinal Ion Transport

Abstract

Epithelia are characterized by a morphological polarity of their cells. This polarity consists mainly of a different arrangement of the plasma membranes at the two cell poles. In the renal proximal tubule and in the small intestine, the apical plasma membrane or brush border is composed of numerous microvilli. At the basal pole of the cell, interdigitations of the cell occur to form the basal infoldings, which are more pronounced in the proximal tubule than in the small intestine.

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Abbreviations

CF-CCP:

Carbonly cyanide p-fluoromethoxy-phenylhydrazone

HEPES:

N-2-hydroxyethylpiperazine-N-2-ethane-sulphonic acid

Tris:

Tris(hydroxymethyl)aminomethane

MES:

2(N-morpholino)-ethane-sulphonic acid

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Author information

Authors and Affiliations

  1. Max-Planck-Institut für Biophysik, Frankfurt/Main, Germany

    R. Kinne & H. Murer

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  1. R. Kinne
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  2. H. Murer
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Editors and Affiliations

  1. Département de Chirurgie Expérimentale, Hôpital Cantonal Universitaire, Lausanne, Switzerland

    J. W. L. Robinson

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Kinne, R., Murer, H. (1976). Polarity of Epithelial Cells in Relation to Transepithelial Transport in Kidney and Intestine. In: Robinson, J.W.L. (eds) Intestinal Ion Transport. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6156-5_5

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  • DOI: https://doi.org/10.1007/978-94-011-6156-5_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-6158-9

  • Online ISBN: 978-94-011-6156-5

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