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Metabolic Effects of Alcohol on the Blood and Bone Marrow

  • Chapter
Metabolic Aspects of Alcoholism

Abstract

It has been increasingly recognized that a kaleidoscopic variety of haematological complications may occur in alcoholic patients. Often it has been difficult to disentangle the relative roles of liver disease, infection, malnutrition, and alcohol ingestion in their pathogenesis. Considerable progress has been made in recent years in delineating the importance of ethanol itself as a haematological toxin. Syndromes which were not even recognized 10 years ago, such as alcohol-induced thrombocytopenia or alcohol-induced sideroblastic anaemia, have been well characterized clinically, reproduced experimentally in human volunteers, and at least partially defined in terms of physiological mechanisms. Other haematological derangements have been identified but remain poorly understood. This chapter will review the current state of knowledge of the various disorders of alcoholics affecting red cells, platelets, and white cells.

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  1. J. Lindenbaum
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Editors and Affiliations

  1. Section of Liver Disease, Nutrition and Alcoholism, Veterans Administration Hospital, New York, USA

    Charles S. Lieber (Chief, Professor of Medicine and Pathology) (Chief, Professor of Medicine and Pathology)

  2. Mount Sinai School of Medicine (CUNY), New York, USA

    Charles S. Lieber (Chief, Professor of Medicine and Pathology) (Chief, Professor of Medicine and Pathology)

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© 1977 MTP Press Limited

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Lindenbaum, J. (1977). Metabolic Effects of Alcohol on the Blood and Bone Marrow. In: Lieber, C.S. (eds) Metabolic Aspects of Alcoholism. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6153-4_8

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  • DOI: https://doi.org/10.1007/978-94-011-6153-4_8

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