Summary
There have been substantial advances in hagfish endocrinology in recent years although restricted to rather specialized areas. Much of the new information has been supported by the availability of new molecular techniques and, as usual for virtually all advances in hagfish biology, has been driven by a continuing appreciation of their unique phylogenetic position and the valuable insights they may contribute to our understanding of evolution. In the pituitary, emphasis has been placed on neurosecretory activity, especially for hypothalamic gonadotrophin-releasing hormone (GnRH) and arginine vasotocin. The most dramatic advances have come in the area of pancreatic hormones where both insulin and insulin-like growth factors (IGFs) have been identified and the full sequence of Myxine insulin confirmed. Distribution is widespread and includes neurones in the brain as well as pancreatic islets. Other endocrine advances are less well documented particularly with respect to biological functions. Of particular note is the identification of substance P and a native natriuretic peptide both as potent vasoregulatory factors.
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Thorndyke, M.C., Falkmer, S. (1998). The Endocrine System of Hagfishes. In: The Biology of Hagfishes. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5834-3_26
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DOI: https://doi.org/10.1007/978-94-011-5834-3_26
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