Abstract
For a century, a major part of physiology and pharmacology has been devoted to the investigation of the mechanisms which transform a stimulus into a message. All the present notions are still based on the revolutionary concept of Paul Ehrlich: “Corpora nun agunt nisi fixata”. Substances cannot act without binding, and, as far as the physical stimuli are concerned, one can consider that the stimulus modifies the binding of pre-existing biochemical components. The aim of this survey, is to illustrate the various mechanisms which transform external stimuli into cellular messages.
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Plenary lecture presented at the 8th GIRI Meeting, December 1994, Jerusalem, Israel.
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References
Barnes, P. J. and Adcock, I. (1993) Anti-inflammatory actions of steroids: molecular mechanisms, Trend Pharmacol. Sci. 14, 436–444.
Edelman, G. M. (1992). Bright air, Brilliant Fire: on the matter of mind. Basic Books Publisher, New York.
Feldman, P. L., Griffith, O. W., and Stuehr, D. J. (1993) The surprising life of nitric oxide, C&EN Dec, 26–38.
Hanoune, J. (1994) Les protéines G, relais de transmission du signal entre récepteur et second messager cellulaire, Prix Nobel de médecine, Médecine/Science 10, 1183–1184.
Kelly, P. and Baulieu, EE (1989) Hormones, Hermann Publisher, Paris.
Loscher, W. and Mevissen, M. (1994) Animal studies on the role of 50/60-Hertz magnetic fields in carcinogenesis, a review, Life Sciences 54, 1531–1543.
Pugh, E. N. and Lamb, T. D. (1993) Amplification and kinetics of the activation steps in phototransduction, Biochim. Biophys Acta. 1141, 111–149.
Sandyk, R.(1992) The influence of the pineal gland on migraine and cluster headaches and effects of treatment with picoTesla magnetic fields. A review, International Journal of Neuroscience, 67, 145–171.
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© 1997 Springer Science+Business Media Dordrecht
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Bonne, C. (1997). From Stimulus to Message in Biological Systems, an Illustrated Survey. In: Bastide, M. (eds) Signals and Images. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5804-6_7
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DOI: https://doi.org/10.1007/978-94-011-5804-6_7
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