Abstract
The aim of this study was to investigate whether there is a correlation between corneal thickness and glycaemic control in insulin-dependent patients. Ultrasound pachymetry and blood glucose measurements were taken in 87 patients three times a day: fasting, and two and four hours after lunch. The patients were divided into three groups: 30 without retinopathy, 30 with background retinopathy and 27 with proliferative retinopathy. Thirty normal age-matched subjects were the control group. No correlation was found between pachymetry values, blood glucose and duration of diabetes in the three groups (p > 0.05). A significant increase in corneal thickness was found in patients with background and proliferative retinopathy compared to the others (p <0.01). There were no differences in corneal thickness between background and proliferative retinopathy (p = 0.74).
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References
N. Busted et al. Clinical observations on the corneal thickness and the corneal endothelium in diabetes mellitus. Br. J. Ophthalmol. 1981;65:687–690.
N. Ehlers. On corneal thickness and intraocular pressure. II: A clinical study on the thickness of the corneal stroma in glaucomatous eyes. Acta Ophthalmol. 1970;48:1107–1112.
F.K. Hansen. A clinical study of the normal human central thickness. Acta Ophthalmol. 1971;48:82.
M. Millidot. Effect of hard contact lenses on corneal sensitivity and thickness. Acta Ophthalmol. 1975;53:576–584.
E. De Cevallos et al. Corneal thickness in glaucoma. Ann. Ophthalmol. 1976;8:177–182.
R. Villasenor et al. Comparison of ultrasonic corneal thickness measurements before and during surgery in the prospective evaluation of radial keratotomy (PERK) study. Ophthalmol. 1986;93:327–330.
J. Ytteborg and C.H. Dohlman. Corneal edema and intraocular pressure. II Clinical results. Arch. Ophthalmol. 1965;74:477.
R.N. Weinreb et al. Maternal corneal thickness during pregnancy. Am. J. Ophthalmol. 1988;105:258–260.
T. Tokoro et al. Central corneal thickness in high myopia. Folia Ophthalmol. Jap. 1971;27:610.
J.H. Lass et al. Morphologic and fluorophotometric analysis of the corneal endothelium in type I diabetes mellitus and cystic fibrosis. Am. J. Ophthalmol. 1985;100:783–788.
R.O. Schultz et al. Corneal endothelial changes in type I and type II diabetes mellitus. Am. J. Ophthalmol. 1984;98:403–410.
B.O. Hedbys and S. Mishima. Flow of water in the corneal stroma. Exp. Eye Res. 1962;1:262–275.
E. Schober et al. Glycosylation of glomerular basement membrane in type I diabetic children. Diabetologia 1982;22:485–487.
J.W. Huff and K. Green. Characteristic of bicarbonate, sodium and chloride fluxes across the rabbit corneal endothelium. Exp. Eye Res. 1983;36:607–615.
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© 1997 Springer Science+Business Media Dordrecht
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Pierro, L., Zaganelli, E., Calori, G., Robino, X., Brancato, R. (1997). Correlation of corneal thickness with blood glucose control in diabetes mellitus. In: Cennamo, G., Rosa, N. (eds) Ultrasonography in Ophthalmology XV. Documenta Ophthalmologica Proceedings Series, vol 61. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5802-2_17
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DOI: https://doi.org/10.1007/978-94-011-5802-2_17
Publisher Name: Springer, Dordrecht
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