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From the Mass Production of Methylococcus Capsulatus to the Efficient Separation and Isolation of Methane Monooxygenase Proteins. Characterization of Novel Intermediates in Substrate Reactions of Methane Monooxygenase

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Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment

Part of the book series: NATO ASI Series ((ASEN2,volume 26))

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Abstract

Methanotrophs are naturally occurring bacteria which utilize methane as their sole source of metabolic energy and carbon.* Due to their ability to catalyze the formation of methanol from methane under ambient conditions, interest has developed over their use as alternative methanol producers.2 In addition, the fact that they oxidize a variety of hydrocarbon substrates other than methane, attracted a lot of attention in their potential exploitation in bioremediation.3 The metalloenzyme system responsible for the conversion of methane to methanol (Reaction 1) in the initial step of their metabolism is methane monooxygenase (MMO).

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Authors and Affiliations

  1. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA

    Katherine E. Liu, Ann M. Valentine, Athanasios Salifoglou & Stephen J. Lippard

  2. the Department of Physics, Emory University, Atlanta, Georgia, 30322, USA

    Danli Wang & Boi H. Huynh

  3. the Department of Biochemistry, Emory University, Atlanta, Georgia, 30322, USA

    Dale E. Edmondson

Authors
  1. Katherine E. Liu
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  2. Ann M. Valentine
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  3. Danli Wang
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  4. Boi H. Huynh
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  5. Dale E. Edmondson
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  6. Athanasios Salifoglou
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  7. Stephen J. Lippard
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Editors and Affiliations

  1. Laboratory of Inorganic and General Chemistry, Department of Chemistry, University of Ioannina, Ioannina, Greece

    Nick D. Hadjiliadis

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© 1997 Springer Science+Business Media Dordrecht

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Liu, K.E. et al. (1997). From the Mass Production of Methylococcus Capsulatus to the Efficient Separation and Isolation of Methane Monooxygenase Proteins. Characterization of Novel Intermediates in Substrate Reactions of Methane Monooxygenase. In: Hadjiliadis, N.D. (eds) Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment. NATO ASI Series, vol 26. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5780-3_16

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  • DOI: https://doi.org/10.1007/978-94-011-5780-3_16

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6440-8

  • Online ISBN: 978-94-011-5780-3

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