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Mild Hypothermic Brain Protection

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Neuroanesthesia

Part of the book series: Developments in Critical Care Medicine and Anesthesiology ((DCCA,volume 32))

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Abstract

Hypothermia as a strategy for intraoperative neuroprotection has been recognized by neuroanesthesiologists for decades. In large part it was abandoned early because it was thought that the principle mechanism by which hypothermia protects is reduction in cerebral metabolic rate (CMR). This implied that deep levels of hypothermia are necessary to provide meaningful benefit. Accordingly, cardiopulmonary bypass would be essential to avoid complications of dysrhythmia and coagulopathy. Beside logistical issues, bypass also requires administration of heparin which considerably increases the complexity of performing surgery on the brain.

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Authors
  1. David S. Warner MD
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Editors and Affiliations

  1. Department of Anesthesiology, The University of Utah School of Medicine, Salt Lake City, Utah, USA

    J. O. Johnson MD, PhD , R. J. Sperry MD, PhD  & T. H. Stanley ,  & 

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© 1997 Springer Science+Business Media Dordrecht

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Warner, D.S. (1997). Mild Hypothermic Brain Protection. In: Johnson, J.O., Sperry, R.J., Stanley, T.H. (eds) Neuroanesthesia. Developments in Critical Care Medicine and Anesthesiology, vol 32. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5774-2_27

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  • DOI: https://doi.org/10.1007/978-94-011-5774-2_27

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6437-8

  • Online ISBN: 978-94-011-5774-2

  • eBook Packages: Springer Book Archive

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