Abstract
Alternative and/or complementary information are provided by functional imaging techniques. Physiological, biochemical, pharmacological variables can be assessed by positron emission tomography (PET) and single photon emission tomography (SPET). Recent technological advances, in particular the implementation of fast acquisition sequences, such as echo-planar technique, allow functional investigation by Magnetic Resonance Imaging (fMRI). For each modality the physical principles and research/clinical applications are presented, relative merits and limitations in assessing functional activity in the brain are discussed in relation to magneto-encephalography (MEG). The combined use of the different information provided by multi-modal bioimaging and bio-signal methods is enhanced by registration techniques, allowing for a spatial correspondence of the multi-modal information. Different approaches to the registration problem are described. Integration of functional imaging techniques and MEG provides an accurate description of cerebral functions with high spatial and temporal resolution, this representing a powerful probe for brain investigation both in basic and clinical neuroscience.
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Gilardi, M.C., Rizzo, G., Lucignani, G., Fazio, F. (1996). Integrating Competing Technologies with MEG. In: Weinstock, H. (eds) SQUID Sensors: Fundamentals, Fabrication and Applications. NATO ASI Series, vol 329. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5674-5_12
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