Abstract
Staphylococcal protein A (SpA) is a cell-wall-bound pathogenicity factor from the bacterium Staphylcoccus aureus. It exhibits tight binding to many IgG, IgA and IgM molecules at site(s) different from antigen-combining site. Because of their small size and immunoglobulin (IgG)-binding activities, domains of protein A are important targets for protein engineering efforts and for the development of computational approaches for de novo protein folding.
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© 1997 Springer Science+Business Media Dordrecht
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Thasiro, M., Tejero, R., Zimmerman, D.E., Celda, B., Nilsson, B., Montelione, G.T. (1997). High Resolution Solution NMR Structure of the Z Domain of Staphylococcal Protein A. Analysis of Secondary Structure for Free Z Domain and Bounded to IgG Antibody. In: Carmona, P., Navarro, R., Hernanz, A. (eds) Spectroscopy of Biological Molecules: Modern Trends. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5622-6_14
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DOI: https://doi.org/10.1007/978-94-011-5622-6_14
Publisher Name: Springer, Dordrecht
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Online ISBN: 978-94-011-5622-6
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