Abstract
Born out of keen observations of antagonistic herbicide interactions, the concept of improving crop tolerance to herbicides with safeners has evolved into a useful agricultural practice (Hatzios and Hoagland, 1989). Safeners (formerly known as antidotes) are chemical compounds that protect crop plants from herbicide injury without reducing weed control (Hatzios and Hoagland, 1989; Kreuz, 1993). Successful safeners are desirable because they allow us to: a) selectively control weeds in botanically related crops; b) improve the margin of crop selectivity of newly developed herbicides; and c) expand the uses of older herbicides (Hatzios and Hoagland, 1989).
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References
Boger, P. and Miller, R. (1994) Protoporphyrin accumulation by peroxidizing herbicides is counteracted by safeners. Zeischrift Naturforschung 49c: 775–780.
Breaux, E.J., Hoobler, M.A., Patanella, J.E. and Leyes, G.A. (1989) Mechanisms of action of thiazole safeners. In: Crop Safeners for Herbicides: Development,Uses, and Mechanisms of Action (K.K. Hatzios and R.E. Hoagland, eds.), 163–175. Academic Press, San Diego.
Devine, M., Duke, S.O. and Fedtke, C. (1993) Physiology of Herbicide Action. Prentice Hall, Englewood Cliffs, NJ.
Donaldson, R.P. and Luster, D.G. (1991) Multiple forms of plant cytochromes P-450. Plant Physiology 96: 669–674.
Durst, F. and Benveniste, I. (1993) Cytochrome P450 in plants. In: Cytochrome P450 (J.B. Schenkman and H. Greim, eds.), 293–310. Springer Verlag, New York.
Farago, S., Brunold, C. and Kreuz, K. (1994) Herbicide safeners and glutathione metabolism. Physiologia Plantarum 91: 537–542.
Gaillard, C., Dufaud, A., Tommasini, R., Kreuz, K., Amrhein, N. and Martinoia, E. (1994) A herbicide antidote (safener) induces the activity of both the herbicide detoxifying enzyme and of a vacuolar transporter for the detoxified herbicide. FEBS Letters 352: 219–221.
Gronwald, J.A., Fuerst, E.P, Eberlein, C.V. and Egli, M.A. (1987) Effect of herbicide antidotes on glutathione content and glutathione transferase activity of sorghum shoots. Pesticide Biochemistry Physiology 29: 66–76.
Hatzios, K.K. and Hoagland, R.E. (Eds.) (1989). Crop Safeners for Herbicides: Development, Uses, and Mechanisms of Action. Academic Press, San Diego.
Hatzios, K.K. (1991) An overview of the mechanisms of action of safeners. Zeischrift Naturforschung 46c: 819–827.
Hatzios, K.K. (1993) Mode of action of naphthalic anhydride as a maize herbicide safener for thifensulfuron-methyl. Proceedings Brighton Crop Protection Conference Weeds 3: 1259–1266.
Hershey, H.P. and Stoner, T.D. (1991) Isolation and characterization of cDNA clones for RNA species induced by substituted benzenesulfonamides in corn. Plant Molecular Biology 17: 679–690.
Jepson, I., Lay, V.J., Holt, D.C., Bright, W.J. and Greenland, A.J. (1994) Cloning and characterization of maize herbicide safener-induced cDNAs encoding subunits of glutathione S-transferase isoforms I, II, and IV. Plant Molecular Biology 26: 1855–1866.
Kreuz, K. (1993) Herbicide safeners: Recent advances and biochemical aspects of their mode of action. Proceedings Brighton Crop Protection Conference Weeds 3: 1249–1258.
Kreuz, K., Gaudin, J., Stingelin, J. and Ebert, E. (1991) Metabolism of the aryloxyphenoxypropanoate herbicide CGA 184927 in wheat, barley and maize: Differential effects of the safener, CGA 185072. Zeischrift Naturforschung 46c: 901–905.
Krueger, J.P., Butz, R.G. and Cork, D.C. (1991) The use of dicamba degrading microorganisms to protect dicamba susceptible plant species. Journal Agricultural Food Chemistry 39: 1000–1003.
Lamoureux, G.L. and Rusness, D.G. (1991) The effect of BAS-145138 safener on chlorimuron ethyl metabolism and toxicity in corn. Zeischrift Naturforschung 46c: 882–886.
Nicolaus, B., Sato, Y., Iida, T., Senoo, S., Wakabayashi, K. and Boger, P. (1995) Enzymatic conversion of isoimide-type peroxidizing herbicides into active imides. Abstracts Weed Science Society America 35: 71.
Omokawa, H., Wu, J. and Hatzios, K.K. (1995) Mechanism of action of (S)-1-(a-methylbenzyl)-3-p-tolyurea, a rice safener against bensulfuron methyl. Abstracts Weed Science Society America 35: 71.
Pickett, C.B. and Lu, A.Y.H. (1989) Glutathione S-transferases: Gene structure, regulation and biological function. Annual Review Biochemistry 58: 743–764.
Sandermann, H. (1992). Plant metabolism of xenobiotics. Trends Biochemical Sciences 17: 82–84.
Timmerman, K.P. (1989) Molecular characterization of corn glutathione S-transferase isozymes involved in herbicide detoxification. Physiologia Plantarum 77: 465–471.
Wiegand, R.C., Shah, D.M., Mozer, T.J., Harding, E.I., Diaz-Collier, J., Sounders, C., Jaworski, E.G. and Tiemeier, D.C. (1986) Messenger RNA encoding a glutathione S-transferase responsible for herbicide tolerance in maize is induced in response to safener treatment. Plant Molecular Biology 7: 235–243.
Wu, J., Meredith, S.A. and Hatzios, K.K. (1995) Investigations on the action of the rice safener fenclorim against pretilachlor injury. Abstracts Weed Science Society America 35: 72.
Yaacoby, T., Hall, J.C. and Stephenson, G.R. (1991) Influence of fenclorazole-ethyl on the metabolism of fenoxaprop-ethyl in wheat, barley and crabgrass. Pesticide Biochemistry Physiology 41: 296–304.
Yenne, S.P. and Hatzios, K.K. (1990) Molecular comparisons of selected herbicides and their safeners by computer-aided molecular modeling. Journal Agricltural Food Chemistry 38: 1950–1956.
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Hatzios, K.K. (1997). Manipulation of Crop Tolerance to Herbicides with Safeners. In: De Prado, R., JorrÃn, J., GarcÃa-Torres, L. (eds) Weed and Crop Resistance to Herbicides. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5538-0_25
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DOI: https://doi.org/10.1007/978-94-011-5538-0_25
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