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Glutathione Transferases and Herbicide Metabolism and Selectivity

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Abstract

In this short paper it is not intended to review glutathione conjugation of herbicides in plants (see Lamoureux and Rusness, 1993). Rather, some of the factors which regulate the role of glutathione transferases (GSTs) in herbicide tolerance and selectivity in plants will be critically evaluated using examples from both the literature and the author’s research group. GSTs catalyse the conjugation of electrophilic substrates with glutathione (GSH) following either nucleophilic substitution or addition, with the resulting conjugates being generally non-toxic. Despite over twenty years of research, GSTs in plants remain poorly characterised even though it is clear that GSTs are present in many, if not all, plant species. With respect to herbicides, several factors appear to regulate their detoxification by plant GSTs and these are now considered in turn.

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© 1997 Springer Science+Business Media Dordrecht

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Edwards, R. (1997). Glutathione Transferases and Herbicide Metabolism and Selectivity. In: De Prado, R., Jorrín, J., García-Torres, L. (eds) Weed and Crop Resistance to Herbicides. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5538-0_11

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  • DOI: https://doi.org/10.1007/978-94-011-5538-0_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6332-6

  • Online ISBN: 978-94-011-5538-0

  • eBook Packages: Springer Book Archive

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