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Biochemical and biophysical principles of hydrogen ion regulation

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Critical Care Nephrology

Abstract

Acid-base balance is as fundamental an aspect of homeostasis as oxygenation or blood pressure. Large living organisms seek to maintain plasma pH within strict tolerance limits. In fact, hydrogen ion (H+) concentration is maintained within the nmol/1 range (36–43 nmol/1). By contrast, other ions are regulated in the mmol/1 range. In the next few sections we will consider the issue of what determines H+ concentration in some detail. Our goal will be to consider the biochemical and biophysical principles of H+ regulation and to apply these concepts to clinical medicine.

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Authors
  1. Martine Leblanc
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  2. John A. Kellum
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© 1998 Springer Science+Business Media Dordrecht

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Leblanc, M., Kellum, J.A. (1998). Biochemical and biophysical principles of hydrogen ion regulation. In: Critical Care Nephrology. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5482-6_23

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  • DOI: https://doi.org/10.1007/978-94-011-5482-6_23

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6306-7

  • Online ISBN: 978-94-011-5482-6

  • eBook Packages: Springer Book Archive

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