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Side Effects of Anti-Inflammatory Drugs IV pp 55–65Cite as

Safety of Non-Steroidal Anti-Inflammatory Drugs during Pregnancy and Lactation

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Abstract

As inhibitors of cyclooxygenase NSAIDs given during pregnancy have the potential to cause adverse maternal and fetal effects. Maternal effects include prolongation of pregnancy and labour, whereas constriction of the ductus arteriosus, renal dysfunction and haemostatic abnormalities can occur in the fetus and neonate. As weak acids, NSAIDs are excreted in small amounts into human breast milk with little risk for adverse effects in the suckling infant.

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Author information

Authors and Affiliations

  1. Department of Rheumatology, University Hospital of Trondheim, N-7006, Trondheim, Norway

    M. E. Østensen

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  1. M. E. Østensen
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Editors and Affiliations

  1. Division of Biomedical Sciences, School of Science and Medicine, Sheffield Hallam University, Sheffield, UK

    K. D. Rainsford

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© 1997 Springer Science+Business Media Dordrecht

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Østensen, M.E. (1997). Safety of Non-Steroidal Anti-Inflammatory Drugs during Pregnancy and Lactation. In: Rainsford, K.D. (eds) Side Effects of Anti-Inflammatory Drugs IV. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5394-2_7

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  • DOI: https://doi.org/10.1007/978-94-011-5394-2_7

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6269-5

  • Online ISBN: 978-94-011-5394-2

  • eBook Packages: Springer Book Archive

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