Abstract
Microfluidic laminate-based structures incorporating hydrodynamic focusing and flow channels with dimensions much less than 1 mm were fabricated and used to transport and analyze blood samples. Optically transparent windows integral to the flow channels were used to intercept the sample streams with a tightly focused diode laser probe beam. The size and structure of the blood cells passing through the laser beam determined the intensity and directional distribution of the scattered light generated. Forward and small angle light scattering channels were used to count and differentiate platelets, red blood cells, and various populations of white blood cells. All the blood samples used were characterized using a commercial hematology analyzer for comparison and validation purposes.
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© 1998 Springer Science+Business Media Dordrecht
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Altendorf, E., Zebert, D., Holl, M., Vannelli, A., Wu, C., Schulte, T. (1998). Results Obtained using A Prototype Microfluidics-Based Hematology Analyzer. In: Harrison, D.J., van den Berg, A. (eds) Micro Total Analysis Systems ’98. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5286-0_17
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DOI: https://doi.org/10.1007/978-94-011-5286-0_17
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-6225-1
Online ISBN: 978-94-011-5286-0
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