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Victorin-induced oat cell death

  • Chapter
Book cover Molecular Genetics of Host-Specific Toxins in Plant Disease

Part of the book series: Developments in Plant Pathology ((DIPP,volume 13))

Abstract

Victoria blight of oats is caused by the fungus Cochliobolus victoriae which is pathogenic because it produces the host-specific toxin, victorin. Oat genotypes are sensitive to victorin if they contain the dominant Vb allele. A 100 kDa protein that binds victorin only in toxin-sensitive (susceptible) genotypes of oats has been identified as the P-protein component of the nuclear-encoded, mitochondrial, glycine decarboxylase complex (GDC). Results have indicated that the 15 kDa H-protein component of the GDC also binds victorin. The GDC, a key component of the photorespiratory cycle, has been shown to be extremely sensitive to the application of victorin both in vivo and in vitro. Recent results have indicated that the cofactor for the P-protein, pyridoxal phosphate, competes with victorin binding in vivo and in vitro and prevents victorin-induced electrolyte leakage. Further, conditions that eliminate photorespiration, protect against victorin-induced symptom development. Thus, a variety of observations indicate a mitochondrial site of action for victorin that is at, or involves, the GDC. Consequently, genetic analyses are being conducted to determine if any of the genes encoding the components of the GDC map to the Vb locus. Our most recent physiological studies have indicated that victorin induces a senescence-like response in sensitive oats including chlorosis, a specific proteolytic degradation of D-ribulose-1,5-bisphosphate carboxylase/oxygenase, and DNA fragmentation. Current studies are directed at characterizing this response and determining what connection exists between victorin’s inhibition of the GDC and this form of programmed cell death.

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Authors and Affiliations

  1. Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR, 97331-2902, USA

    T. J. Wolpert, D. A. Navarre & J. M. Lorang

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  1. T. J. Wolpert
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  2. D. A. Navarre
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  3. J. M. Lorang
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Editors and Affiliations

  1. Faculty of Agriculture, Tottori University, Koyama, Tottori, Japan

    Keisuke Kohmoto

  2. Department of Plant Pathology, Cornell University, Ithaca, New York, USA

    Olen C. Yoder

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© 1998 Springer Science+Business Media Dordrecht

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Wolpert, T.J., Navarre, D.A., Lorang, J.M. (1998). Victorin-induced oat cell death. In: Kohmoto, K., Yoder, O.C. (eds) Molecular Genetics of Host-Specific Toxins in Plant Disease. Developments in Plant Pathology, vol 13. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5218-1_12

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  • DOI: https://doi.org/10.1007/978-94-011-5218-1_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6197-1

  • Online ISBN: 978-94-011-5218-1

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