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MALDI MS of Oligo and Polysaccharides

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Selected Topics in Mass Spectrometry in the Biomolecular Sciences

Part of the book series: NATO ASI Series ((ASIC,volume 504))

Abstract

Most problems in carbohydrate analysis arise from investigation of biological systems, so that we need highly sensitive methods of analysis. In the last two years, some papers on PSD MALDI MS of oligosaccharides have been published [1–4] and it appears that PSD may became the method of choice to distinguish isomeric oligosaccharides. In figure 1 the PSD spectra of the four isomeric lacto-N-fucopentaoses (LNFP) shown in table I are reported. The spectra are quite different allowing easily the differentiation, though the structures in table 1 are very similar.

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Authors and Affiliations

  1. Istituto per la Chimica e la Tecnologia dei Materiali Polimerici, Viale A. Doria 6, 95125, Catania, Italy

    D. Garozzo

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  1. D. Garozzo
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Editors and Affiliations

  1. Medical School, University of Texas, Houston, Texas, USA

    Richard M. Caprioli

  2. SESMA-C.N.R., Napoli, Italy

    Antonio Malorni

  3. Dipartimento di Chimica, Arcavacata di Rende, Università della Calabria, Italy

    Giovanni Sindona

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© 1997 Springer Science+Business Media Dordrecht

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Garozzo, D. (1997). MALDI MS of Oligo and Polysaccharides. In: Caprioli, R.M., Malorni, A., Sindona, G. (eds) Selected Topics in Mass Spectrometry in the Biomolecular Sciences. NATO ASI Series, vol 504. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5165-8_25

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  • DOI: https://doi.org/10.1007/978-94-011-5165-8_25

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6171-1

  • Online ISBN: 978-94-011-5165-8

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