Abstract
Subcutaneous injection of EHS extract in combination with 1 μM bFGF induced fat pad formation in the area where the meshwork of basement membrane components was reconstituted in vivo. Histological section of the pad showed well developed adipocytes delivered with blood cells. This process was preceded by microvascularization of the area within 2 days. Combination of EHS extract with IGF-1 and growth hormone induced muscle fiber in addition to fat tissue. Injection of erythropoietin together with EHS extract resulted in angiogenesis at periphery of the reconstituted basement membrane.
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© 1998 Springer Science+Business Media Dordrecht
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Kawaguchi, N., Nicodemou-Lena, E., Toriyama, K., Torii, S., Kitagawa, Y. (1998). Matricrine Effect of Basement Membrane Components on De Novo Formation of Mesenchymal Tissues. In: Nagai, K., Wachi, M. (eds) Animal Cell Technology: Basic & Applied Aspects. Animal Cell Technology: Basic & Applied Aspects, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5161-0_44
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DOI: https://doi.org/10.1007/978-94-011-5161-0_44
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