Abstract
Angiogenesis, the growth of new blood vessels, occurs in various physiological conditions such as embryonic development, ovulation and wound healing. Angiogenesis is, however, strictly controlled under normal conditions in the adult. On the other hand, uncontrolled angiogenesis is often associated with diseases such as diabetic retinopathy, rheumatoid arthritis and solid tumor. Particularly, angiogenesis is necessary for the continued growth of solid tumor [1]. Folkman introduced the new concept that an antiangiogenesis strategy might represent a novel therapeutic approach for the treatment of solid tumor [2]. This has led to a search for angiogenesis inhibitors which might be used therapeutically.
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© 1998 Springer Science+Business Media Dordrecht
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Shibata, T., Otsuka, T., Terano, H., Okuhara, M. (1998). New Angiogenesis Inhibitors of Microbial Origin. In: Nagai, K., Wachi, M. (eds) Animal Cell Technology: Basic & Applied Aspects. Animal Cell Technology: Basic & Applied Aspects, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5161-0_18
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DOI: https://doi.org/10.1007/978-94-011-5161-0_18
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