Skip to main content

Radiation therapy for age-related subfoveal neovascular membranes

  • Chapter
Retinal Pigment Epithelium and Macular Diseases

Part of the book series: Documenta Ophthalmologica Proceedings Series ((DOPS,volume 62))

  • 203 Accesses

Abstract

Age-related macular degeneration is the leading cause of blindness in patients older than 50 years of age in the Western world. The natural visual course for patients with subfoveal membranes is poor. Retrospective studies have shown that about 60-70% of affected have final acuity of 0.1 or worse within 12-18 months1-4. Although previous studies have shown some long-term benefit of laser treatment for subfoveal CNV, the patient has to be prepared for a large decrease in visual acuity immediately following therapy5-7.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bressler, N.M., Bressler, S.B., Fine, S.L. Age-related macular degeneration. Sury Ophthalmol. 1988; 32: 375–412.

    Article  CAS  Google Scholar 

  2. Bressler, N.M., Frost, L.A., Bressler, S.B., Murphy, R.P., Fine, S.L. Natural course of poorly defined choroidal neovascularisation associated with macular degeneration. Arch Ophthalmol. 1988; 106: 1537–1542.

    Article  PubMed  CAS  Google Scholar 

  3. Guyer, D.R., Fine, S.L., Maguire, M.G., Hawkins, B.S., Owens, S.L., Murphy, R.P. Subfoveal choroidal neovascular membranes in age-related macular degeneration. Visual prognosis in eyes with relative good visual acuity. Arch Ophthalmol. 1986; 104: 702–705.

    Article  PubMed  CAS  Google Scholar 

  4. Singerman, L.J., Stockfish, J.H. Natural history of subfoveal pigment epithelial detachments associated with subfoveal or unindentifiable choroidal neovascularisation complicating age-related macular degeneration. Graefe’s Arch Clin Exp Ophthalmol. 1989; 227: 501–507.

    Article  CAS  Google Scholar 

  5. Coscas, G., Soubrane, G., Ramahefasolo, C., Fardeau, C. Perifoveal laser treatment for subfoveal choroidal new vessels in age-related macular degeneration: results of a randomized clinical trial. Arch Ophthalmol. 1991; 109: 1258–1265.

    Article  PubMed  CAS  Google Scholar 

  6. Macular Photocoagulation Study Group. Laser photocoagulation of subfoveal neovascular lesions in age-related macular degeneration. Arch Ophthalmol. 1991; 109: 1220–1231.

    Article  Google Scholar 

  7. Macular Photocoagulation Study Group. Subfoveal neovascular lesions in age-related macular degeneration: guidelines for evaluation and treatment in the macular photocoagulation study. Arch Ophthalmol. 1991; 109: 1242–1257.

    Article  Google Scholar 

  8. Chakravarthy, U., Houston, R.F., Archer, D.B. Treatment of age-related subfoveal neovascular membranes by teletherapy: a pilot study. Br J Ophthalmol. 1993; 77: 265–273.

    Article  PubMed  CAS  Google Scholar 

  9. Bergink, G.J., Deutman, A.F., van den Broek, J.F., van Daal, W.A., van der Maazen, R.W. Radiation therapy for subfoveal choroidal neovascular membranes in age-related macular degeneration. A pilot study. Graefes Arch Clin Exp Ophthalmol. 1994; 232: 591–598.

    Article  PubMed  CAS  Google Scholar 

  10. Bergink, G.J., Deutman, A.F., van den Broek, J.F., van Daal, W.A., van der Maazen, R.W. Radiation therapy for age-related subfoveal choroidal membranes. A pilot study. Doc Ophthalmol. 1995; 90: 67–74.

    Article  PubMed  CAS  Google Scholar 

  11. Hart, P.M., Archer, D.B., Chakravarthy, U. Asymmetry of disciform scarring in bilateral disease when one eye is treated with radiotherapy. Br J Ophthalmol. 1995; 70: 562–568.

    Article  Google Scholar 

  12. Valmaggia, C., Bischoff, P., Ries, G. Niedrig dosierte Radiotherapie der subfoveolären Neovaskularisationen bei altersabhängiger Makuladegeneration. Vorläufige Resultate. Klin Monatsbl Augenheilkd. 1995; 206: 343–346.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Snyders, B., Renard, L., Koninckx, C., Cioffi, M. (1998). Radiation therapy for age-related subfoveal neovascular membranes. In: Coscas, G., Piccolino, F.C. (eds) Retinal Pigment Epithelium and Macular Diseases. Documenta Ophthalmologica Proceedings Series, vol 62. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5137-5_67

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-5137-5_67

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6160-5

  • Online ISBN: 978-94-011-5137-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics