Abstract
Indocyanine (ICG) angiography is shown to be helpful in identifying choroidal new vessels when occult on fluorescein angiography1-5. Isolated occult choroidal neovascularization (CNV) or leakage of undetermined source (type II of the MPS classification) are not associated with serous haemorrhagic, or fibrovascular pigment epithelium detachment. On early phase ICG angiography, occult CNV may be converted into a well-defined net in about 40% of cases6,7. This conversion allows a good delination and definition of the limits of the neo vascular complex. This early net is more often identified using scanning laser ophthalmoscope technology while using infrared fundus cameras. The identification of isolated occult CNV is based on the visualization in the late phases of hyperfluorescent plaque with hyperfluorescence. The signification of this late staining plaque is still controversial.
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Flower, R.W. High-speed human choroidal angiography using indocyanine green dye and a continuous light source. Doc Ophthalmol Proc Ser. 1976; 9: 59–66.
Destro, M., Puliafito, C. Indocyanine green videoangiography of choroidal neovascularization. Ophthalmology. 1989; 96: 846–853.
Yannuzzi, L.A., Slakter, J.S., Sorenson, J.A., Guyer, D.R., Orlock, D.A. Digital indocyanine green video angiography and choroidal neovascularization. Retina. 1992; 12: 191–223.
Scheider, A., Kaboth, A., Neubauser, R. Detection of subretinal neovascular membranes with indocyanine green and an infrared scanning laser ophthalmoscope. Am J Ophthalmol. 1992; 113: 45–51.
Regillo, C.D., Benson, W.E., Maguire, J.F., Annesley, W.H. Indocyanine green angiography and occult choroidal neovascularization. Ophthalmology. 1994; 101: 280–288.
Lim, J.I., Sternberg, P., Capone, A., Aaberg, T.M., Gilman, J.P. Selective use of indocyanine green angiography for occult choroidal neovascularization. Am J Ophthalmol. 1995; 120: 75–82.
Wolf, S., Knabben, H., Krombech, H., Schaaf, A., Stolbach, U., Reim, M. Indocyanine green angiography in patients with occult choroidal neovascularization. Ger J Ophthalmol. 1996; 5: 251–256.
Soubrane, G., Coscas, G., Kuhn, D., Secretan, M., Herpe, C. Indocyanine green videoangiography in normal. 2nd International Symposium on indocyanine green angiography, Nara, Japan, 8/4/1995.
Guyer, D.R., Slakter, J.S., Hanutsaha, P. Indocyanine green videoangiography of drusen as a possible predictive indicator of exudative maculopathy. Annual Meeting of the American Academy of Ophthalmology. 1996, abstract book p. 125.
Slakter, J.S., Yannuzzi, L.A., Sorenson, J.A., Guyer, D.R., Hu, A.C., Orlock, D.A. A pilot study of indocyanine green videoangiography-guided laser photocoagulation of occult choroidal neovascularization in age-related macular degeneration. Arch Ophthalmol. 1994; 112: 465–472.
Quaranta, M., Krott, R., Soubrane, G., Coscas, G. Circulation choroïdienne et vidéoangiographie au vert d’indocyanine dans la néovascularisation choroïdienne occulte. Ophtalmologie. 1995; 9: 200–202.
Pauleikhoff, P., Chen, J.C., Chisholm, I.M., Bird, A.C. Choroidal perfusion abnormality with age-related Bruch’s membrane change. Am J Ophthalmol. 1990; 109: 211–217.
Bird, A.C. Pathogenesis of retinal pigment epithelial detachment in the elderly: the relevance of Bruch’s membrane change. Eye. 1991; 51: 1–12.
Polkinghorne, P., Capon, M.R., Berninger, T., Lyness, A.L., Sehmi, K., Bird, A.C. Sorsby’s fundus dystrophy. A clinical study. Ophthalmology. 1989; 96: 1763–1768.
Piguet, B., Palmwang, I.B., Chisholm, I.M., Minassian, D., Bird, A.C. Evolution of age-related macular degeneration with choroidal perfusion abnormality. Am J Ophthalmol. 1992; 113: 657–663.
Green, W.R. Age-related macular degeneration histopatologic studies: the 1992 Lorenz E. Zimerman Lecture. Ophthalmology. 1993; 100: 1519–1535.
Korte, G.E., Repucci, V., Henkind, P. RPE destruction causes choriocapillary atrophy. Invest Ophthalmol Vis Sci. 1984; 25: 1135–1145.
Bressler, N.M., Silva, J.C., Bressler, S.B., Fine, S.L., Green, W.R. Clinicopathologic correlation of drusen and retinal pigment epithelial abnormalities in age-related macular degeneration. Retina. 1994; 14: 130–142.
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Soubrane, G., Coscas, G., Kuhn, D., Quaranta, M. (1998). Isolated occult choroidal neovascularization: comparison between early and late phases of ICG angiography. In: Coscas, G., Piccolino, F.C. (eds) Retinal Pigment Epithelium and Macular Diseases. Documenta Ophthalmologica Proceedings Series, vol 62. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5137-5_58
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DOI: https://doi.org/10.1007/978-94-011-5137-5_58
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