Indocyanine green angiographic findings in a case of Harada’s disease

Abstract

Vogt-Koyanagi-Harada (VKH) syndrome is a multisystemic disease involving melanocytic organs such as eyes, ears, skin and meninges. The ocular involvement is a bilateral panuveitis associated with exudative retinal detachments that occurs most often in darkly pigmented individuals and is probably the result of an autoimmune process directed primarily aganist choroidal melanocytes^1,2. The diagnostic criteria for VKH syndrome, established by the American Uveitis Society, include at least three of the following features: (a) bilateral iridocyclitis; (b) posterior uveitis, including exudative retinal detachment or ‘sunset glow’ fundus; (c) central nervous system findings, including headache, meningismus, tinnitus, dysacousis, neck stifness, or cerebrospinal fluid pleocytosis; (d) cutaneous findings, including alopecia, poliosis, or vitiligo³. There ahve been few reported studies concerning indocyanin green (ICG) angiography in VKH syndrome^4,5) We report a case of VKH syndrome studied with ICG angiography before and after resolution of the subretinal exudation.