Abstract
Trials of systemic administration of interferon (IFN) for treatment of choroidal neovascularization (CNV) have been widely adapted1,2. We have demonstrated that IFN has a stimulating effect on retinal pigment epithelium (RPE) proliferation in an experimental model of choroidal neovascularization3. Systemic administration of IFN, however, remains a problem with respect to side effects and a high cost. We therefore performed animal experiments to clarify the effect of local administration of human IFN-β on repair of the RPE after laser photocoagulation (PC).
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© 1998 Springer Science+Business Media Dordrecht
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Kimoto, T., Takahashi, K., Tobe, T., Uyama, M., Sone, S. (1998). Local administration of interferon-beta promotes proliferation of retinal pigment epithelial cells in repairing process after laser photocoagulation. In: Coscas, G., Piccolino, F.C. (eds) Retinal Pigment Epithelium and Macular Diseases. Documenta Ophthalmologica Proceedings Series, vol 62. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5137-5_15
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DOI: https://doi.org/10.1007/978-94-011-5137-5_15
Publisher Name: Springer, Dordrecht
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